Gene description for FAM179B
Gene name family with sequence similarity 179, member B
Gene symbol FAM179B
Other names/aliases KIAA0423
Species Homo sapiens
 Database cross references - FAM179B
ExoCarta ExoCarta_23116
Vesiclepedia VP_23116
Entrez Gene 23116
HGNC 19959
UniProt Q9Y4F4  
 FAM179B identified in sEVs derived from the following tissue/cell type
Urine 21595033    
Urine 21595033    
Urine 21595033    
 Gene ontology annotations for FAM179B
Molecular Function
    protein binding GO:0005515 IPI
    microtubule binding GO:0008017 IBA
Biological Process
    microtubule cytoskeleton organization GO:0000226 IBA
    positive regulation of microtubule polymerization GO:0031116 ISS
    axoneme assembly GO:0035082 ISS
    cilium assembly GO:0060271 IMP
    non-motile cilium assembly GO:1905515 ISS
Subcellular Localization
    microtubule GO:0005874 ISS
    cytoplasmic microtubule GO:0005881 IBA
    cilium GO:0005929 IBA
    cilium GO:0005929 ISS
    axoneme GO:0005930 IDA
    ciliary basal body GO:0036064 ISS
 Experiment description of studies that identified FAM179B in sEVs
1
Experiment ID 193
MISEV standards
EM
Biophysical techniques
CD63|CD9
Enriched markers
PHB
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 194
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 195
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for FAM179B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CEP135  
Proximity Label-MS Homo sapiens
2 EFNA1  
Affinity Capture-MS Homo sapiens
3 GDI1 2664
Affinity Capture-MS Homo sapiens
4 PSMB3 5691
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which FAM179B is involved
No pathways found





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