Gene description for Slc39a10
Gene name solute carrier family 39 (zinc transporter), member 10
Gene symbol Slc39a10
Other names/aliases 2900042E17Rik
5430433I10
mKIAA1265
Species Mus musculus
 Database cross references - Slc39a10
ExoCarta ExoCarta_227059
Vesiclepedia VP_227059
Entrez Gene 227059
UniProt Q6P5F6  
 Slc39a10 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Slc39a10
Molecular Function
    zinc ion transmembrane transporter activity GO:0005385 IBA
    zinc ion transmembrane transporter activity GO:0005385 IMP
    zinc ion transmembrane transporter activity GO:0005385 ISO
    zinc ion transmembrane transporter activity GO:0005385 ISS
    protein binding GO:0005515 IPI
    protein tyrosine phosphatase activator activity GO:0008160 IMP
    monoatomic cation:bicarbonate symporter activity GO:0140410 IBA
Biological Process
    epithelial to mesenchymal transition GO:0001837 IDA
    epithelial to mesenchymal transition GO:0001837 ISO
    epithelial to mesenchymal transition GO:0001837 ISS
    negative regulation of B cell apoptotic process GO:0002903 IMP
    intracellular zinc ion homeostasis GO:0006882 IMP
    intracellular monoatomic cation homeostasis GO:0030003 IBA
    positive regulation of B cell proliferation GO:0030890 IMP
    positive regulation of B cell receptor signaling pathway GO:0050861 IMP
    zinc ion transmembrane transport GO:0071577 ISO
    zinc ion transmembrane transport GO:0071577 ISS
    zinc ion import across plasma membrane GO:0071578 IBA
    zinc ion import across plasma membrane GO:0071578 IMP
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 ISO
    apical plasma membrane GO:0016324 IDA
    apical plasma membrane GO:0016324 ISO
 Experiment description of studies that identified Slc39a10 in sEVs
1
Experiment ID 907
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Slc39a10
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Sstr3  
Proximity Label-MS Mus musculus
View the network image/svg+xml
 Pathways in which Slc39a10 is involved
No pathways found





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