Gene description for Wdr36
Gene name WD repeat domain 36
Gene symbol Wdr36
Other names/aliases 5730444A13Rik
Ta-wdrp
Species Mus musculus
 Database cross references - Wdr36
ExoCarta ExoCarta_225348
Vesiclepedia VP_225348
Entrez Gene 225348
 Wdr36 identified in sEVs derived from the following tissue/cell type
Neural stem cells 25242146    
 Gene ontology annotations for Wdr36
Biological Process
    retina homeostasis GO:0001895 IMP
    rRNA processing GO:0006364 IBA
    regulation of axon extension GO:0030516 IMP
    ribosomal small subunit biogenesis GO:0042274 ISO
Subcellular Localization
    small-subunit processome GO:0032040 IBA
    small-subunit processome GO:0032040 ISO
    Pwp2p-containing subcomplex of 90S preribosome GO:0034388 IBA
 Experiment description of studies that identified Wdr36 in sEVs
1
Experiment ID 263
MISEV standards
Biophysical techniques
CD63|CD9
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25242146    
Organism Mus musculus
Experiment description Extracellular Vesicles from Neural Stem Cells Transfer IFN-? via Ifngr1 to Activate Stat1 Signaling in Target Cells
Authors "Chiara Cossetti, Nunzio Iraci, Tim R. Mercer, Tommaso Leonardi, Emanuele Alpi, Denise Drago, Clara Alfaro-Cervello, Harpreet K. Saini, Matthew P. Davis, Julia Schaeffer, Beatriz Vega, Matilde Stefanini, CongJian Zhao, Werner Muller, Jose Manuel Garcia-Verdugo, Suresh Mathivanan, Angela Bachi, Anton J. Enright, John S. Mattick, Stefano Pluchino"
Journal name Molecular Cell
Publication year 2014
Sample Neural stem cells
Sample name NPCs - Th1 treated
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Wdr36
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Ddb1 13194
Affinity Capture-MS Mus musculus
2 Foxp3  
Affinity Capture-MS Mus musculus
3 Fancd2  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Wdr36 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here