Gene description for Ttc7
Gene name tetratricopeptide repeat domain 7
Gene symbol Ttc7
Other names/aliases 1110035E02Rik
1700007L07Rik
Ttc7a
fsn
hea
Species Mus musculus
 Database cross references - Ttc7
ExoCarta ExoCarta_225049
Vesiclepedia VP_225049
Entrez Gene 225049
UniProt Q8BGB2  
 Ttc7 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Ttc7
Biological Process
    intracellular iron ion homeostasis GO:0006879 IMP
    hemopoiesis GO:0030097 IMP
    phosphatidylinositol phosphate biosynthetic process GO:0046854 IBA
    protein localization to plasma membrane GO:0072659 IBA
    protein localization to plasma membrane GO:0072659 ISO
    protein localization to plasma membrane GO:0072659 ISS
Subcellular Localization
    cytoplasm GO:0005737 IEA
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified Ttc7 in sEVs
1
Experiment ID 907
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Ttc7
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 9430020K01Rik  
Co-fractionation Mus musculus
2 Exosc9  
Co-fractionation Mus musculus
3 Mios  
Co-fractionation Mus musculus
4 Iqsec1  
Co-fractionation Mus musculus
5 Lmnb2  
Co-fractionation Mus musculus
View the network image/svg+xml
 Pathways in which Ttc7 is involved
No pathways found





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