Gene description for Vtn
Gene name	vitronectin
Gene symbol	Vtn
Other names/aliases	AI256434 Vn
Species	Mus musculus
Database cross references - Vtn
ExoCarta	ExoCarta_22370
Vesiclepedia	VP_22370
Entrez Gene	22370
UniProt	P29788
Vtn identified in sEVs derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Vtn

Molecular Function     scavenger receptor activity GO:0005044 IEA     integrin binding GO:0005178 IBA     integrin binding GO:0005178 IEA     integrin binding GO:0005178 ISO     extracellular matrix structural constituent GO:0005201 RCA     collagen binding GO:0005518 IEA     collagen binding GO:0005518 ISO     heparin binding GO:0008201 IEA     heparin binding GO:0008201 ISO     polysaccharide binding GO:0030247 IEA     identical protein binding GO:0042802 IEA     identical protein binding GO:0042802 ISO     extracellular matrix binding GO:0050840 IBA     extracellular matrix binding GO:0050840 IDA Biological Process     immune response GO:0006955 IEA     cell-matrix adhesion GO:0007160 IBA     cell-matrix adhesion GO:0007160 IDA     cell-matrix adhesion GO:0007160 ISO     positive regulation of cell-substrate adhesion GO:0010811 IDA     negative regulation of endopeptidase activity GO:0010951 ISO     positive regulation of smooth muscle cell migration GO:0014911 IEA     positive regulation of smooth muscle cell migration GO:0014911 ISO     vesicle-mediated transport GO:0016192 IEA     cell migration GO:0016477 IEA     cell migration GO:0016477 ISO     regulation of cell adhesion GO:0030155 ISO     extracellular matrix organization GO:0030198 IDA     positive regulation of protein binding GO:0032092 ISO     cell adhesion mediated by integrin GO:0033627 IBA     cell adhesion mediated by integrin GO:0033627 IEA     cell adhesion mediated by integrin GO:0033627 ISO     endodermal cell differentiation GO:0035987 IEA     endodermal cell differentiation GO:0035987 ISO     positive regulation of receptor-mediated endocytosis GO:0048260 IEA     positive regulation of receptor-mediated endocytosis GO:0048260 ISO     oligodendrocyte differentiation GO:0048709 IDA     positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 IEA     positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 ISO     protein polymerization GO:0051258 IEA     protein polymerization GO:0051258 ISO     negative regulation of fibrinolysis GO:0051918 NAS     smooth muscle cell-matrix adhesion GO:0061302 IEA     smooth muscle cell-matrix adhesion GO:0061302 ISO     liver regeneration GO:0097421 IEA     liver regeneration GO:0097421 ISO Subcellular Localization     basement membrane GO:0005604 IEA     basement membrane GO:0005604 ISO     extracellular space GO:0005615 IBA     extracellular space GO:0005615 IEA     extracellular space GO:0005615 ISO     endoplasmic reticulum GO:0005783 ISO     Golgi lumen GO:0005796 IEA     Golgi lumen GO:0005796 ISO     extracellular matrix GO:0031012 IDA     intracellular membrane-bounded organelle GO:0043231 ISO     rough endoplasmic reticulum lumen GO:0048237 IEA     rough endoplasmic reticulum lumen GO:0048237 ISO     collagen-containing extracellular matrix GO:0062023 HDA     collagen-containing extracellular matrix GO:0062023 IBA     collagen-containing extracellular matrix GO:0062023 ISO     collagen-containing extracellular matrix GO:0062023 NAS     protein complex involved in cell-matrix adhesion GO:0098637 ISO     peptidase inhibitor complex GO:1904090 ISO