Gene description for Tnfrsf10b
Gene name	tumor necrosis factor receptor superfamily, member 10b
Gene symbol	Tnfrsf10b
Other names/aliases	DR5 KILLER Ly98 MK TRAILR2 TRICK2A TRICK2B TRICKB
Species	Mus musculus
Database cross references - Tnfrsf10b
ExoCarta	ExoCarta_21933
Vesiclepedia	VP_21933
Entrez Gene	21933
UniProt	Q9QZM4
Tnfrsf10b identified in sEVs derived from the following tissue/cell type
Breast cancer cells	34112803
Breast cancer cells	34112803

Gene ontology annotations for Tnfrsf10b

Molecular Function     protease binding GO:0002020 ISO     cysteine-type endopeptidase activator activity involved in apoptotic process GO:0008656 RCA     TRAIL receptor activity GO:0036463 ISO     identical protein binding GO:0042802 ISO     TRAIL binding GO:0045569 RCA Biological Process     apoptotic process GO:0006915 RCA     extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 ISO     response to endoplasmic reticulum stress GO:0034976 ISS     TRAIL-activated apoptotic signaling pathway GO:0036462 IBA     regulation of apoptotic process GO:0042981 RCA     positive regulation of apoptotic process GO:0043065 IBA     negative regulation of multicellular organismal process GO:0051241 IEA     intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 ISS Subcellular Localization     Golgi apparatus GO:0005794 ISO     cytosol GO:0005829 ISO     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 ISO     cell surface GO:0009986 IBA     cell surface GO:0009986 ISO     membrane GO:0016020 IEA     membrane raft GO:0045121 ISO