Gene description for Taok1
Gene name	TAO kinase 1
Gene symbol	Taok1
Other names/aliases	2810468K05Rik AU020252 D130018F14Rik Map3k16 Markk Psk2 mKIAA1361
Species	Mus musculus
Database cross references - Taok1
ExoCarta	ExoCarta_216965
Vesiclepedia	VP_216965
Entrez Gene	216965
UniProt	Q5F2E8
Taok1 identified in sEVs derived from the following tissue/cell type
Macrophages	23658846
Macrophages	23658846
Macrophages	23658846

Gene ontology annotations for Taok1

Molecular Function     protein kinase activity GO:0004672 ISO     protein serine/threonine kinase activity GO:0004674 IBA     protein serine/threonine kinase activity GO:0004674 ISO     protein serine/threonine kinase activity GO:0004674 ISS     3-phosphoinositide-dependent protein kinase activity GO:0004676 IEA     DNA-dependent protein kinase activity GO:0004677 IEA     AMP-activated protein kinase activity GO:0004679 IEA     eukaryotic translation initiation factor 2alpha kinase activity GO:0004694 IEA     ribosomal protein S6 kinase activity GO:0004711 IEA     ATP binding GO:0005524 IEA     kinase activity GO:0016301 ISO     protein kinase binding GO:0019901 ISO     protein kinase activator activity GO:0030295 ISO     myosin V binding GO:0031489 ISO     histone H3S10 kinase activity GO:0035175 IEA     histone H3T11 kinase activity GO:0035402 IEA     histone H3T6 kinase activity GO:0035403 IEA     histone H2AXS139 kinase activity GO:0035979 IEA     alpha-tubulin binding GO:0043014 IEA     alpha-tubulin binding GO:0043014 ISO     protein serine/threonine kinase activator activity GO:0043539 ISO     histone H3S28 kinase activity GO:0044022 IEA     histone H4S1 kinase activity GO:0044023 IEA     histone H2AS1 kinase activity GO:0044024 IEA     histone H2BS14 kinase activity GO:0044025 IEA     beta-tubulin binding GO:0048487 IEA     beta-tubulin binding GO:0048487 ISO     histone H3T3 kinase activity GO:0072354 IEA     histone H2AS121 kinase activity GO:0072371 IEA     Rho-dependent protein serine/threonine kinase activity GO:0072518 IEA     protein serine kinase activity GO:0106310 IEA     histone H2BS36 kinase activity GO:0140823 IEA     histone H3S57 kinase activity GO:0140855 IEA     histone H3T45 kinase activity GO:0140857 IEA     histone H2AT120 kinase activity GO:1990244 IEA Biological Process     microtubule cytoskeleton organization GO:0000226 IEA     microtubule cytoskeleton organization GO:0000226 ISO     DNA repair GO:0006281 IEA     chromatin remodeling GO:0006338 IEA     DNA damage response GO:0006974 ISO     DNA damage response GO:0006974 ISS     negative regulation of microtubule depolymerization GO:0007026 IEA     negative regulation of microtubule depolymerization GO:0007026 ISO     mitotic G2 DNA damage checkpoint signaling GO:0007095 ISO     mitotic G2 DNA damage checkpoint signaling GO:0007095 ISS     phosphorylation GO:0016310 ISO     central nervous system neuron development GO:0021954 IMP     central nervous system neuron development GO:0021954 ISO     positive regulation of stress-activated MAPK cascade GO:0032874 IBA     positive regulation of stress-activated MAPK cascade GO:0032874 ISO     positive regulation of stress-activated MAPK cascade GO:0032874 ISS     regulation of actin cytoskeleton organization GO:0032956 ISO     positive regulation of JNK cascade GO:0046330 IBA     positive regulation of JNK cascade GO:0046330 ISO     positive regulation of JNK cascade GO:0046330 ISS     regulation of cytoskeleton organization GO:0051493 IBA     regulation of cytoskeleton organization GO:0051493 ISO     regulation of cytoskeleton organization GO:0051493 ISS     neuron cellular homeostasis GO:0070050 IEA     neuron cellular homeostasis GO:0070050 ISO     regulation of microtubule cytoskeleton organization GO:0070507 ISO     execution phase of apoptosis GO:0097194 ISO     execution phase of apoptosis GO:0097194 ISS     positive regulation of protein acetylation GO:1901985 IEA     positive regulation of protein acetylation GO:1901985 ISO Subcellular Localization     cytoplasm GO:0005737 IBA     microtubule cytoskeleton GO:0015630 IEA     microtubule cytoskeleton GO:0015630 ISO     perinuclear region of cytoplasm GO:0048471 IEA     perinuclear region of cytoplasm GO:0048471 ISO