Gene description for Nlgn2
Gene name	neuroligin 2
Gene symbol	Nlgn2
Other names/aliases	NL2
Species	Mus musculus
Database cross references - Nlgn2
ExoCarta	ExoCarta_216856
Vesiclepedia	VP_216856
Entrez Gene	216856
UniProt	Q69ZK9
Nlgn2 identified in sEVs derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Nlgn2

Molecular Function     protein binding GO:0005515 IPI     neurexin family protein binding GO:0042043 IPI     identical protein binding GO:0042802 IPI     cell adhesion molecule binding GO:0050839 IPI Biological Process     thigmotaxis GO:0001966 ISO     thigmotaxis GO:0001966 ISS     regulation of respiratory gaseous exchange by nervous system process GO:0002087 IGI     neuron cell-cell adhesion GO:0007158 ISO     neuron cell-cell adhesion GO:0007158 ISS     synapse assembly GO:0007416 ISO     synapse assembly GO:0007416 ISS     jump response GO:0007630 ISO     jump response GO:0007630 ISS     positive regulation of cell population proliferation GO:0008284 IEA     positive regulation of cell population proliferation GO:0008284 ISO     sensory perception of pain GO:0019233 IMP     positive regulation of insulin secretion GO:0032024 IEA     positive regulation of insulin secretion GO:0032024 ISO     positive regulation of synaptic transmission, GABAergic GO:0032230 IMP     protein localization to cell surface GO:0034394 IDA     protein localization to cell surface GO:0034394 IMP     social behavior GO:0035176 ISO     social behavior GO:0035176 ISS     protein localization to synapse GO:0035418 IDA     locomotory exploration behavior GO:0035641 IMP     modulation of chemical synaptic transmission GO:0050804 IGI     synapse organization GO:0050808 ISO     synapse organization GO:0050808 ISS     neuromuscular process controlling balance GO:0050885 IMP     synaptic transmission, GABAergic GO:0051932 IDA     synaptic transmission, GABAergic GO:0051932 IGI     synaptic transmission, GABAergic GO:0051932 IMP     positive regulation of synapse assembly GO:0051965 ISO     positive regulation of synapse assembly GO:0051965 ISS     positive regulation of synaptic transmission, glutamatergic GO:0051968 IMP     positive regulation of dendritic spine development GO:0060999 IEA     positive regulation of dendritic spine development GO:0060999 ISO     terminal button organization GO:0072553 ISO     terminal button organization GO:0072553 ISS     neurotransmitter-gated ion channel clustering GO:0072578 IDA     neurotransmitter-gated ion channel clustering GO:0072578 IGI     neurotransmitter-gated ion channel clustering GO:0072578 IMP     postsynaptic membrane assembly GO:0097104 IDA     presynaptic membrane assembly GO:0097105 IDA     presynaptic membrane assembly GO:0097105 IMP     presynaptic membrane assembly GO:0097105 ISO     gephyrin clustering involved in postsynaptic density assembly GO:0097116 IDA     gephyrin clustering involved in postsynaptic density assembly GO:0097116 IGI     gephyrin clustering involved in postsynaptic density assembly GO:0097116 IMP     postsynaptic density protein 95 clustering GO:0097119 IDA     positive regulation of inhibitory postsynaptic potential GO:0097151 IMP     positive regulation of inhibitory postsynaptic potential GO:0097151 ISO     postsynaptic specialization assembly GO:0098698 IDA     postsynaptic specialization assembly GO:0098698 IMP     presynapse assembly GO:0099054 IDA     insulin metabolic process GO:1901142 IEA     insulin metabolic process GO:1901142 ISO     positive regulation of protein localization to synapse GO:1902474 ISO     positive regulation of protein localization to synapse GO:1902474 ISO     positive regulation of t-SNARE clustering GO:1904034 IEA     positive regulation of t-SNARE clustering GO:1904034 ISO     inhibitory synapse assembly GO:1904862 IDA     regulation of presynapse assembly GO:1905606 IEA     regulation of presynapse assembly GO:1905606 ISO     regulation of AMPA receptor activity GO:2000311 IMP     positive regulation of excitatory postsynaptic potential GO:2000463 IMP     positive regulation of synaptic vesicle clustering GO:2000809 IDA Subcellular Localization     plasma membrane GO:0005886 ISO     cell surface GO:0009986 IDA     cell surface GO:0009986 IDA     cell surface GO:0009986 ISO     cell surface GO:0009986 ISS     axon GO:0030424 IDA     dendrite GO:0030425 IDA     presynaptic membrane GO:0042734 IEA     dendritic shaft GO:0043198 IEA     dendritic shaft GO:0043198 ISO     synapse GO:0045202 IDA     postsynaptic membrane GO:0045211 ISO     postsynaptic membrane GO:0045211 ISS     excitatory synapse GO:0060076 IC     excitatory synapse GO:0060076 ISO     inhibitory synapse GO:0060077 IC     inhibitory synapse GO:0060077 ISO     ribbon synapse GO:0097470 IEA     ribbon synapse GO:0097470 ISO     glycinergic synapse GO:0098690 IDA     glycinergic synapse GO:0098690 IMP     dopaminergic synapse GO:0098691 IDA     GABA-ergic synapse GO:0098982 IDA     GABA-ergic synapse GO:0098982 IDA     GABA-ergic synapse GO:0098982 IMP     GABA-ergic synapse GO:0098982 ISO     postsynaptic specialization membrane GO:0099634 IBA     postsynaptic specialization membrane GO:0099634 IDA     postsynaptic specialization membrane GO:0099634 ISO