Gene description for Lrrtm3
Gene name leucine rich repeat transmembrane neuronal 3
Gene symbol Lrrtm3
Other names/aliases 9630044H04Rik
Species Mus musculus
 Database cross references - Lrrtm3
ExoCarta ExoCarta_216028
Entrez Gene 216028
UniProt Q8BZ81  
 Lrrtm3 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Lrrtm3
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    positive regulation of beta-amyloid formation GO:1902004 ISO
    positive regulation of synapse assembly GO:0051965 IDA
Subcellular Localization
    integral component of membrane GO:0016021 ISS
    plasma membrane GO:0005886 IEA
    synapse GO:0045202 IEA
    membrane GO:0016020 IEA
    postsynaptic membrane GO:0045211 IEA
    cell junction GO:0030054 IEA
 Experiment description of studies that identified Lrrtm3 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Lrrtm3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Lrrtm3 is involved
No pathways found





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