Gene description for Sdc1
Gene name syndecan 1
Gene symbol Sdc1
Other names/aliases AA408134
AA409076
CD138
Sstn
Synd
Synd1
syn-1
Species Mus musculus
 Database cross references - Sdc1
ExoCarta ExoCarta_20969
Entrez Gene 20969
UniProt P18828  
 Sdc1 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Sdc1
Molecular Function
    glycoprotein binding GO:0001948 IPI
    protein C-terminus binding GO:0008022 ISO
Biological Process
    myoblast development GO:0048627 IDA
    inflammatory response GO:0006954 ISO
    positive regulation of exosomal secretion GO:1903543 ISO
    cell migration GO:0016477 IBA
    canonical Wnt signaling pathway GO:0060070 IMP
    positive regulation of extracellular exosome assembly GO:1903553 ISO
Subcellular Localization
    external side of plasma membrane GO:0009897 IDA
    integral component of membrane GO:0016021 IEA
    extracellular region GO:0005576 IEA
    protein complex GO:0043234 ISO
    extracellular exosome GO:0070062 ISO
    focal adhesion GO:0005925 ISO
    cell surface GO:0009986 ISO
    membrane GO:0016020 IEA
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Sdc1 in exosomes
1
Experiment ID 210
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD81|FLOT1
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Sdc1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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