Gene description for Nid1
Gene name nidogen 1
Gene symbol Nid1
Other names/aliases A630025O17
Species Mus musculus
 Database cross references - Nid1
ExoCarta ExoCarta_18073
Entrez Gene 18073
UniProt P10493  
 Nid1 identified in exosomes derived from the following tissue/cell type
Embryonic fibroblasts 18494037    
 Gene ontology annotations for Nid1
Molecular Function
    proteoglycan binding GO:0043394 ISO
    extracellular matrix binding GO:0050840 IDA
    protein binding GO:0005515 IPI
    laminin-1 binding GO:0043237 IDA
    collagen binding GO:0005518 ISO
    laminin binding GO:0043236 ISO
    calcium ion binding GO:0005509 IEA
Biological Process
    positive regulation of cell-substrate adhesion GO:0010811 IDA
    extracellular matrix organization GO:0030198 IDA
    glomerular basement membrane development GO:0032836 IMP
    cell-matrix adhesion GO:0007160 IDA
    cell adhesion GO:0007155 IEA
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    extracellular region GO:0005576 IEA
    basal lamina GO:0005605 IDA
    extracellular matrix GO:0031012 ISO
    cell periphery GO:0071944 IDA
    proteinaceous extracellular matrix GO:0005578 IDA
    basement membrane GO:0005604 TAS
 Experiment description of studies that identified Nid1 in exosomes
Experiment ID 73
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 18494037    
Organism Mus musculus
Experiment description Difference gel electrophoresis analysis of Ras-transformed fibroblast cell-derived exosomes.
Authors Ji H, Erfani N, Tauro BJ, Kapp EA, Zhu HJ, Moritz RL, Lim JW, Simpson RJ
Journal name ELEC
Publication year 2008
Sample Embryonic fibroblasts
Sample name NIH3T3
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA]
Western blotting
 Protein-protein interactions for Nid1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LAMC1 3915
Reconstituted Complex Homo sapiens
2 COL1A1 1277
Reconstituted Complex Homo sapiens
3 COL4A1 1282
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which Nid1 is involved
Degradation of the extracellular matrix IEA Reactome
Laminin interactions IEA Reactome

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here