Gene description for Clec10a
Gene name C-type lectin domain family 10, member A
Gene symbol Clec10a
Other names/aliases CD301a
M-ASGP-BP-1
Mgl
Mgl1
Species Mus musculus
 Database cross references - Clec10a
ExoCarta ExoCarta_17312
Vesiclepedia VP_17312
Entrez Gene 17312
UniProt P49300  
 Clec10a identified in sEVs derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Clec10a
Molecular Function
    D-mannose binding GO:0005537 IBA
    carbohydrate binding GO:0030246 IEA
    pattern recognition receptor activity GO:0038187 IBA
    fucose binding GO:0042806 IBA
Biological Process
    connective tissue replacement involved in inflammatory response wound healing GO:0002248 IMP
    immune response GO:0006955 IBA
Subcellular Localization
    external side of plasma membrane GO:0009897 IBA
    membrane GO:0016020 IEA
 Experiment description of studies that identified Clec10a in sEVs
1
Experiment ID 210
MISEV standards
EM
Biophysical techniques
CD81|FLOT1
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors "Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL."
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Clec10a
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Clec10a is involved
No pathways found





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