Gene description for Slco1a2
Gene name solute carrier organic anion transporter family, member 1A2
Gene symbol Slco1a2
Other names/aliases Oatp2
Slc21a5
Slco1a4
Species Rattus norvegicus
 Database cross references - Slco1a2
ExoCarta ExoCarta_170698
Vesiclepedia VP_170698
Entrez Gene 170698
UniProt O35913  
 Slco1a2 identified in sEVs derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Slco1a2
Molecular Function
    organic anion transmembrane transporter activity GO:0008514 IDA
    organic anion transmembrane transporter activity GO:0008514 ISO
    bile acid transmembrane transporter activity GO:0015125 IBA
    bile acid transmembrane transporter activity GO:0015125 IDA
    sodium-independent organic anion transmembrane transporter activity GO:0015347 IBA
    transmembrane transporter activity GO:0022857 IEA
    transmembrane transporter activity GO:0022857 ISO
Biological Process
    monoatomic ion transport GO:0006811 IEA
    monoatomic anion transport GO:0006820 ISO
    bile acid and bile salt transport GO:0015721 IBA
    sodium-independent organic anion transport GO:0043252 IBA
    sodium-independent organic anion transport GO:0043252 IDA
    response to estrogen GO:0043627 IEP
    transmembrane transport GO:0055085 IEA
    cellular response to xenobiotic stimulus GO:0071466 IEP
Subcellular Localization
    plasma membrane GO:0005886 IEA
    plasma membrane GO:0005886 ISO
    basal plasma membrane GO:0009925 IDA
    basal plasma membrane GO:0009925 ISO
    membrane GO:0016020 ISO
    basolateral plasma membrane GO:0016323 IBA
 Experiment description of studies that identified Slco1a2 in sEVs
1
Experiment ID 35
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|CD81|CD63
Enriched markers
✔
HSPA5
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Slco1a2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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