Gene description for Lamp1 |
Gene name |
lysosomal-associated membrane protein 1 |
Gene symbol |
Lamp1 |
Other names/aliases |
AI196048 CD107a Lamp-1 |
Species |
Mus musculus |
Database cross references - Lamp1 |
ExoCarta |
ExoCarta_16783 |
Entrez Gene |
16783 |
UniProt |
P11438
|
Lamp1 identified in exosomes derived from the following tissue/cell type |
Fibroblasts
|
23260141
|
Mammary adenocarcinoma cells
|
11231627
|
Microglia
|
16081791
|
Gene ontology annotations for Lamp1 |
|
Experiment description of studies that identified Lamp1 in exosomes |
1 |
Experiment ID |
210 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✘
|
EV Cytosolic markers |
✔
CD81|FLOT1
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
23260141
|
Organism |
Mus musculus |
Experiment description |
Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration. |
Authors |
Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL. |
Journal name |
Cell
|
Publication year |
2012 |
Sample |
Fibroblasts |
Sample name |
Normal-Fibroblasts (L cells) |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
2 |
Experiment ID |
23 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✘
|
EV Cytosolic markers |
✘
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Western blotting Immunoelectron Microscopy
|
PubMed ID |
11231627
|
Organism |
Mus musculus |
Experiment description |
Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. |
Authors |
Wolfers J, Lozier A, Raposo G, Regnault A, Thery C, Masurier C, Flament C, Pouzieux S, Faure F, Tursz T, Angevin E, Amigorena S, Zitvogel L |
Journal name |
NM
|
Publication year |
2001 |
Sample |
Mammary adenocarcinoma cells |
Sample name |
TS/A (H-2d) P815 mastocytoma cells (H-2d) |
Isolation/purification methods |
Differential centrifugation Sucrose density gradient |
Flotation density |
1.14 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Western blotting Immunoelectron Microscopy |
|
|
3 |
Experiment ID |
14 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
RAB7|RAB11
|
EV Cytosolic markers |
✔
CD9|CD63|LAMP1|LAMP2
|
EV Membrane markers |
✔
DNM
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Western blotting
|
PubMed ID |
16081791
|
Organism |
Mus musculus |
Experiment description |
Proteomic analysis of microglia-derived exosomes: metabolic role of the aminopeptidase CD13 in neuropeptide catabolism. |
Authors |
Potolicchio I, Carven GJ, Xu X, Stipp C, Riese RJ, Stern LJ, Santambrogio L |
Journal name |
JIMMU
|
Publication year |
2005 |
Sample |
Microglia |
Sample name |
N9 |
Isolation/purification methods |
Differential centrifugation Sucrose density gradient |
Flotation density |
1.15 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry [LCQ DECA XP] Western blotting |
|
|
Protein-protein interactions for Lamp1 |
|
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
No interactions are found.
|
|
Pathways in which Lamp1 is involved |
No pathways found
|
|
|