Gene description for FREM3
Gene name FRAS1 related extracellular matrix 3
Gene symbol FREM3
Other names/aliases -
Species Homo sapiens
 Database cross references - FREM3
ExoCarta ExoCarta_166752
Entrez Gene 166752
HGNC 25172
MIM 608946
UniProt P0C091  
 FREM3 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for FREM3
Molecular Function
    metal ion binding GO:0046872 IEA
Biological Process
    cell communication GO:0007154 IEA
    cell adhesion GO:0007155 NAS
Subcellular Localization
    basement membrane GO:0005604 ISS
    integral component of membrane GO:0016021 IEA
    extracellular matrix GO:0031012 TAS
    extracellular space GO:0005615 IDA
 Experiment description of studies that identified FREM3 in exosomes
1
Experiment ID 126
ISEV standards
EV Biophysical techniques
GAPDH
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for FREM3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which FREM3 is involved
No pathways found





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