Gene description for Itm2b
Gene name
integral membrane protein 2B
Gene symbol
Itm2b
Other names/aliases
AI256040 Bri Bri2 Bricd2b D14Sel6 E25BMM imBRI2
Species
Mus musculus
Database cross references - Itm2b
ExoCarta
ExoCarta_16432
Vesiclepedia
VP_16432
Entrez Gene
16432
UniProt
O89051
Itm2b identified in sEVs derived from the following tissue/cell type
Colon cancer cells
37309723
T-cell lymphoma cells
37309723
Gene ontology annotations for Itm2b
Experiment description of studies that identified Itm2b in sEVs
1
Experiment ID
907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
Colon cancer cells
Sample name
C26
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
T-cell lymphoma cells
Sample name
EL4
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for Itm2b
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
Ngly1
Co-fractionation
Mus musculus
2
Nphs2
Affinity Capture-MS
Mus musculus
3
Tmem173
Proximity Label-MS
Mus musculus
4
Lmo2
Two-hybrid
Mus musculus
5
Tmem38b
Co-fractionation
Mus musculus
6
Sepp1
Co-fractionation
Mus musculus
7
Unk
Affinity Capture-RNA
Mus musculus
8
Fancd2
Affinity Capture-MS
Mus musculus
View the network
image/svg+xml
Pathways in which Itm2b is involved
No pathways found