Gene description for Icam2
Gene name intercellular adhesion molecule 2
Gene symbol Icam2
Other names/aliases CD102
Icam-2
Ly-60
Species Mus musculus
 Database cross references - Icam2
ExoCarta ExoCarta_15896
Vesiclepedia VP_15896
Entrez Gene 15896
UniProt P35330  
 Icam2 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Icam2
Molecular Function
    integrin binding GO:0005178 IBA
    integrin binding GO:0005178 IEA
    integrin binding GO:0005178 ISO
    protein binding GO:0005515 IPI
Biological Process
    cell adhesion GO:0007155 IBA
    cell-cell adhesion GO:0098609 IEA
Subcellular Localization
    uropod GO:0001931 IDA
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    microvillus GO:0005902 IDA
    cleavage furrow GO:0032154 IEA
    cleavage furrow GO:0032154 ISO
    cell periphery GO:0071944 IDA
 Experiment description of studies that identified Icam2 in sEVs
1
Experiment ID 907
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Icam2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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