Gene description for Slc36a1
Gene name solute carrier family 36 (proton/amino acid symporter), member 1
Gene symbol Slc36a1
Other names/aliases Lyaat1
Species Rattus norvegicus
 Database cross references - Slc36a1
ExoCarta ExoCarta_155205
Vesiclepedia VP_155205
Entrez Gene 155205
UniProt Q924A5  
 Slc36a1 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Slc36a1
Molecular Function
    amino acid:proton symporter activity GO:0005280 IBA
    amino acid:proton symporter activity GO:0005280 IDA
    amino acid:proton symporter activity GO:0005280 ISO
    proline:proton symporter activity GO:0005297 IDA
    proline:proton symporter activity GO:0005297 IEA
    proline:proton symporter activity GO:0005297 ISO
    L-tyrosine transmembrane transporter activity GO:0005302 ISO
    proton transmembrane transporter activity GO:0015078 IDA
    neutral L-amino acid transmembrane transporter activity GO:0015175 IDA
    neutral L-amino acid transmembrane transporter activity GO:0015175 NAS
    L-alanine transmembrane transporter activity GO:0015180 IBA
    L-alanine transmembrane transporter activity GO:0015180 IEA
    L-alanine transmembrane transporter activity GO:0015180 ISO
    glycine transmembrane transporter activity GO:0015187 IBA
    glycine transmembrane transporter activity GO:0015187 IEA
    glycine transmembrane transporter activity GO:0015187 ISO
    L-proline transmembrane transporter activity GO:0015193 IBA
    L-proline transmembrane transporter activity GO:0015193 IEA
    L-proline transmembrane transporter activity GO:0015193 ISO
    alanine transmembrane transporter activity GO:0022858 ISO
Biological Process
    taurine transmembrane transport GO:0015734 IEA
    taurine transmembrane transport GO:0015734 ISO
    neutral amino acid transport GO:0015804 IDA
    L-alanine transport GO:0015808 IBA
    L-alanine transport GO:0015808 IEA
    L-alanine transport GO:0015808 ISO
    glycine transport GO:0015816 IBA
    glycine transport GO:0015816 IEA
    glycine transport GO:0015816 ISO
    proline transport GO:0015824 IEA
    proline transport GO:0015824 ISO
    alanine transport GO:0032328 ISO
    proline transmembrane transport GO:0035524 IBA
    proline transmembrane transport GO:0035524 IEA
    amino acid import across plasma membrane GO:0089718 IEA
    amino acid import across plasma membrane GO:0089718 ISO
    proton transmembrane transport GO:1902600 IBA
    proton transmembrane transport GO:1902600 IDA
    proton transmembrane transport GO:1902600 IEA
    proton transmembrane transport GO:1902600 ISO
Subcellular Localization
    lysosome GO:0005764 IDA
    lysosomal membrane GO:0005765 IEA
    vacuolar membrane GO:0005774 IBA
    endoplasmic reticulum GO:0005783 IEA
    endoplasmic reticulum GO:0005783 ISO
    plasma membrane GO:0005886 IDA
    membrane GO:0016020 IEA
    apical plasma membrane GO:0016324 IEA
 Experiment description of studies that identified Slc36a1 in sEVs
1
Experiment ID 90
MISEV standards
EM
Biophysical techniques
HSC70|HSP90|TSG101|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E"
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Slc36a1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here