Gene description for Foxq1
Gene name forkhead box Q1
Gene symbol Foxq1
Other names/aliases HFH-1
Hfh1
Hfh1l
sa
Species Mus musculus
 Database cross references - Foxq1
ExoCarta ExoCarta_15220
Vesiclepedia VP_15220
Entrez Gene 15220
UniProt O70220  
 Foxq1 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Foxq1
Molecular Function
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IDA
    DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IBA
    DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227 IDA
    sequence-specific double-stranded DNA binding GO:1990837 ISO
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IDA
    regulation of transcription by RNA polymerase II GO:0006357 IBA
    anatomical structure morphogenesis GO:0009653 IBA
    cell differentiation GO:0030154 IBA
    hair follicle morphogenesis GO:0031069 IMP
    negative regulation of neuron apoptotic process GO:0043524 ISO
Subcellular Localization
    nucleus GO:0005634 IEA
 Experiment description of studies that identified Foxq1 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Foxq1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Ssbp3  
Two-hybrid Mus musculus
2 Ssbp2  
Two-hybrid Mus musculus
View the network image/svg+xml
 Pathways in which Foxq1 is involved
No pathways found





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