Gene description for Fcer1g
Gene name Fc receptor, IgE, high affinity I, gamma polypeptide
Gene symbol Fcer1g
Other names/aliases AI573376
CD23
FcR-gamma
FcR[g]
FcRgamma
Fce1g
FcepsilonRI
Ly-50
Species Mus musculus
 Database cross references - Fcer1g
ExoCarta ExoCarta_14127
Entrez Gene 14127
UniProt P20491  
 Fcer1g identified in exosomes derived from the following tissue/cell type
Microglia 16081791    
 Gene ontology annotations for Fcer1g
Molecular Function
    protein binding GO:0005515 IPI
    IgE binding GO:0019863 IMP
    IgE receptor activity GO:0019767 IMP
    IgG binding GO:0019864 IMP
    transmembrane signaling receptor activity GO:0004888 IEA
Biological Process
    positive regulation of mast cell cytokine production GO:0032765 IMP
    negative regulation of mast cell apoptotic process GO:0033026 IMP
    Fc-gamma receptor signaling pathway GO:0038094 IDA
    positive regulation of mast cell degranulation GO:0043306 IMP
    Fc-epsilon receptor signaling pathway GO:0038095 IMP
    integrin-mediated signaling pathway GO:0007229 IMP
    mast cell activation GO:0045576 IMP
    positive regulation of type I hypersensitivity GO:0001812 IMP
    innate immune response GO:0045087 IMP
    cell surface receptor signaling pathway GO:0007166 IMP
    Fc receptor mediated stimulatory signaling pathway GO:0002431 IMP
    antigen processing and presentation of exogenous peptide antigen via MHC class I GO:0042590 IMP
    regulation of immune response GO:0050776 IMP
    positive regulation of interleukin-6 production GO:0032755 IMP
    positive regulation of type IIa hypersensitivity GO:0001798 IMP
    immunoglobulin mediated immune response GO:0016064 IMP
    neutrophil chemotaxis GO:0030593 IMP
    T cell differentiation involved in immune response GO:0002292 IMP
    positive regulation of tumor necrosis factor production GO:0032760 IMP
    positive regulation of immune response GO:0050778 IMP
    regulation of platelet activation GO:0010543 IMP
    protein localization to plasma membrane GO:0072659 IDA
    positive regulation of interleukin-10 production GO:0032733 IMP
    antigen processing and presentation of exogenous peptide antigen via MHC class II GO:0019886 IMP
    neutrophil activation involved in immune response GO:0002283 IMP
    signal transduction GO:0007165 IDA
    serotonin secretion by platelet GO:0002554 IMP
    positive regulation of type III hypersensitivity GO:0001805 IMP
    defense response to bacterium GO:0042742 IMP
    phagocytosis, engulfment GO:0006911 IMP
    positive regulation of phagocytosis GO:0050766 IMP
Subcellular Localization
    cell surface GO:0009986 ISO
    integral component of membrane GO:0016021 IEA
    integral component of plasma membrane GO:0005887 IDA
    external side of plasma membrane GO:0009897 IDA
    Fc-epsilon receptor I complex GO:0032998 IMP
    membrane GO:0016020 IEA
    plasma membrane GO:0005886 IDA
    membrane raft GO:0045121 TAS
 Experiment description of studies that identified Fcer1g in exosomes
1
Experiment ID 14
ISEV standards
EM
EV Biophysical techniques
RAB7|RAB11
EV Cytosolic markers
CD9|CD63|LAMP1|LAMP2
EV Membrane markers
DNM
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 16081791    
Organism Mus musculus
Experiment description Proteomic analysis of microglia-derived exosomes: metabolic role of the aminopeptidase CD13 in neuropeptide catabolism.
Authors Potolicchio I, Carven GJ, Xu X, Stipp C, Riese RJ, Stern LJ, Santambrogio L
Journal name JIMMU
Publication year 2005
Sample Microglia
Sample name N9
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA XP]
Western blotting
 Protein-protein interactions for Fcer1g
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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