Gene description for Apoa5
Gene name	apolipoprotein A-V
Gene symbol	Apoa5
Other names/aliases	apo-AV apoA-V
Species	Rattus norvegicus
Database cross references - Apoa5
ExoCarta	ExoCarta_140638
Vesiclepedia	VP_140638
Entrez Gene	140638
UniProt	Q9QUH3
Apoa5 identified in sEVs derived from the following tissue/cell type
Hepatocytes	19367702

Gene ontology annotations for Apoa5

Molecular Function     phospholipid binding GO:0005543 IBA     phospholipid binding GO:0005543 ISO     enzyme activator activity GO:0008047 ISO     heparin binding GO:0008201 IEA     heparin binding GO:0008201 ISO     lipid binding GO:0008289 IEA     lipid binding GO:0008289 ISO     enzyme binding GO:0019899 ISO     phosphatidylcholine binding GO:0031210 IEA     phosphatidylcholine binding GO:0031210 ISO     lipase binding GO:0035473 IEA     lipase binding GO:0035473 ISO     low-density lipoprotein particle receptor binding GO:0050750 IEA     low-density lipoprotein particle receptor binding GO:0050750 ISO     phosphatidylcholine-sterol O-acyltransferase activator activity GO:0060228 IBA     lipase activator activity GO:0060229 ISO     lipoprotein lipase activator activity GO:0060230 IEA     lipoprotein lipase activator activity GO:0060230 ISO     lipoprotein particle receptor binding GO:0070325 ISO     cholesterol transfer activity GO:0120020 IBA Biological Process     triglyceride metabolic process GO:0006641 ISO     triglyceride metabolic process GO:0006641 ISO     lipid transport GO:0006869 IEA     lipid transport GO:0006869 IMP     lipid transport GO:0006869 ISO     cholesterol metabolic process GO:0008203 IBA     response to hormone GO:0009725 IEP     positive regulation of triglyceride catabolic process GO:0010898 IEA     positive regulation of triglyceride catabolic process GO:0010898 ISO     positive regulation of very-low-density lipoprotein particle remodeling GO:0010902 IEA     positive regulation of very-low-density lipoprotein particle remodeling GO:0010902 ISO     triglyceride catabolic process GO:0019433 IEA     triglyceride catabolic process GO:0019433 ISO     animal organ regeneration GO:0031100 IEP     cholesterol efflux GO:0033344 IBA     phospholipid efflux GO:0033700 IBA     triglyceride-rich lipoprotein particle remodeling GO:0034370 IEA     triglyceride-rich lipoprotein particle remodeling GO:0034370 ISO     lipoprotein metabolic process GO:0042157 IEA     tissue regeneration GO:0042246 IEA     tissue regeneration GO:0042246 ISO     cholesterol homeostasis GO:0042632 IEA     cholesterol homeostasis GO:0042632 ISO     positive regulation of fatty acid biosynthetic process GO:0045723 IEA     positive regulation of fatty acid biosynthetic process GO:0045723 ISO     positive regulation of lipid catabolic process GO:0050996 ISO     positive regulation of lipoprotein lipase activity GO:0051006 ISO     acylglycerol homeostasis GO:0055090 IBA     acylglycerol homeostasis GO:0055090 ISO     triglyceride homeostasis GO:0070328 IEA     triglyceride homeostasis GO:0070328 ISO Subcellular Localization     extracellular region GO:0005576 ISO     extracellular space GO:0005615 IDA     extracellular space GO:0005615 ISO     early endosome GO:0005769 IEA     late endosome GO:0005770 IEA     Golgi apparatus GO:0005794 IEA     very-low-density lipoprotein particle GO:0034361 IBA     very-low-density lipoprotein particle GO:0034361 IEA     very-low-density lipoprotein particle GO:0034361 ISO     low-density lipoprotein particle GO:0034362 ISO     high-density lipoprotein particle GO:0034364 IBA     high-density lipoprotein particle GO:0034364 IEA     high-density lipoprotein particle GO:0034364 ISO     chylomicron GO:0042627 IBA     chylomicron GO:0042627 IEA     chylomicron GO:0042627 ISO     extracellular vesicle GO:1903561 IBA