Gene description for COMP
Gene name	cartilage oligomeric matrix protein
Gene symbol	COMP
Other names/aliases	EDM1 EPD1 MED PSACH THBS5
Species	Homo sapiens
Database cross references - COMP
ExoCarta	ExoCarta_1311
Entrez Gene	1311
HGNC	2227
MIM	600310
UniProt	P49747
COMP identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable
Prostate cancer cells	25844599

Gene ontology annotations for COMP

Molecular Function     extracellular matrix structural constituent GO:0005201 IEA     calcium ion binding GO:0005509 IDA     collagen binding GO:0005518 IDA     protein binding GO:0005515 IPI     heparan sulfate proteoglycan binding GO:0043395 IDA     protease binding GO:0002020 IPI     heparin binding GO:0008201 IDA Biological Process     growth plate cartilage development GO:0003417 IEA     extracellular matrix organization GO:0030198 TAS     limb development GO:0060173 IDA     organ morphogenesis GO:0009887 TAS     cell adhesion GO:0007155 IEA     apoptotic process GO:0006915 IEA     skeletal system development GO:0001501 TAS     negative regulation of apoptotic process GO:0043066 IDA Subcellular Localization     proteinaceous extracellular matrix GO:0005578 IEA     extracellular matrix GO:0031012 IDA     extracellular region GO:0005576 TAS     extracellular exosome GO:0070062 IDA     extracellular space GO:0005615 IDA