Gene description for Ctss
Gene name	cathepsin S
Gene symbol	Ctss
Other names/aliases	-
Species	Mus musculus
Database cross references - Ctss
ExoCarta	ExoCarta_13040
Vesiclepedia	VP_13040
Entrez Gene	13040
UniProt	O70370
Ctss identified in sEVs derived from the following tissue/cell type
Microglia	16081791

Gene ontology annotations for Ctss

Molecular Function     fibronectin binding GO:0001968 ISO     cysteine-type endopeptidase activity GO:0004197 EXP     cysteine-type endopeptidase activity GO:0004197 IBA     cysteine-type endopeptidase activity GO:0004197 ISO     collagen binding GO:0005518 ISO     peptidase activity GO:0008233 IDA     cysteine-type peptidase activity GO:0008234 ISO     laminin binding GO:0043236 ISO     proteoglycan binding GO:0043394 ISO Biological Process     proteolysis GO:0006508 IDA     proteolysis GO:0006508 ISO     response to acidic pH GO:0010447 ISO     protein processing GO:0016485 ISO     antigen processing and presentation of exogenous peptide antigen via MHC class II GO:0019886 ISO     antigen processing and presentation of exogenous peptide antigen via MHC class II GO:0019886 ISS     collagen catabolic process GO:0030574 ISO     basement membrane disassembly GO:0034769 IMP     basement membrane disassembly GO:0034769 ISO     bone resorption GO:0045453 ISO     antigen processing and presentation of peptide antigen GO:0048002 ISO     positive regulation of inflammatory response GO:0050729 IGI     proteolysis involved in protein catabolic process GO:0051603 IBA     proteolysis involved in protein catabolic process GO:0051603 IMP     proteolysis involved in protein catabolic process GO:0051603 ISO     positive regulation of cation channel activity GO:2001259 IDA     positive regulation of cation channel activity GO:2001259 ISO Subcellular Localization     extracellular space GO:0005615 IBA     extracellular space GO:0005615 ISO     extracellular space GO:0005615 ISS     lysosome GO:0005764 IBA     lysosome GO:0005764 IDA     lysosome GO:0005764 ISO     late endosome GO:0005770 ISO     cell surface GO:0009986 ISO     membrane GO:0016020 IDA     early endosome lumen GO:0031905 TAS     intracellular membrane-bounded organelle GO:0043231 ISO     phagocytic vesicle GO:0045335 ISO     phagocytic vesicle GO:0045335 ISS