Gene description for Ctcf
Gene name	CCCTC-binding factor
Gene symbol	Ctcf
Other names/aliases	AW108038
Species	Mus musculus
Database cross references - Ctcf
ExoCarta	ExoCarta_13018
Vesiclepedia	VP_13018
Entrez Gene	13018
UniProt	Q61164
Ctcf identified in sEVs derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Ctcf

Molecular Function     transcription cis-regulatory region binding GO:0000976 ISO     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IEA     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 ISO     cis-regulatory region sequence-specific DNA binding GO:0000987 IDA     transcription coregulator binding GO:0001221 IEA     transcription coregulator binding GO:0001221 ISO     DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227 IEA     DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227 ISO     DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 IBA     DNA binding GO:0003677 IDA     chromatin binding GO:0003682 IDA     DNA-binding transcription factor activity GO:0003700 ISO     protein binding GO:0005515 IPI     chromatin insulator sequence binding GO:0043035 IEA     chromatin insulator sequence binding GO:0043035 ISO     sequence-specific DNA binding GO:0043565 IDA     sequence-specific DNA binding GO:0043565 ISO     metal ion binding GO:0046872 IEA     DNA-binding transcription factor binding GO:0140297 ISO     chromatin loop anchoring activity GO:0140587 IEA     chromatin loop anchoring activity GO:0140587 ISO     sequence-specific double-stranded DNA binding GO:1990837 ISO Biological Process     negative regulation of transcription by RNA polymerase II GO:0000122 IMP     negative regulation of transcription by RNA polymerase II GO:0000122 ISO     in utero embryonic development GO:0001701 IMP     chromatin organization GO:0006325 IMP     DNA methylation-dependent constitutive heterochromatin formation GO:0006346 IMP     regulation of DNA-templated transcription GO:0006355 IDA     regulation of transcription by RNA polymerase II GO:0006357 IBA     mitochondrion organization GO:0007005 IMP     chromosome segregation GO:0007059 IEA     heart development GO:0007507 IMP     negative regulation of cell population proliferation GO:0008285 ISO     negative regulation of cell population proliferation GO:0008285 ISS     gene expression GO:0010467 IMP     positive regulation of gene expression GO:0010628 IMP     positive regulation of gene expression GO:0010628 ISO     negative regulation of gene expression GO:0010629 IMP     epigenetic regulation of gene expression GO:0040029 IDA     epigenetic regulation of gene expression GO:0040029 ISO     negative regulation of gene expression via chromosomal CpG island methylation GO:0044027 IMP     negative regulation of DNA-templated transcription GO:0045892 ISO     positive regulation of DNA-templated transcription GO:0045893 ISO     positive regulation of transcription by RNA polymerase II GO:0045944 IEA     positive regulation of transcription by RNA polymerase II GO:0045944 ISO     cardiac muscle cell differentiation GO:0055007 IMP     cardiac muscle cell development GO:0055013 IMP     random inactivation of X chromosome GO:0060816 TAS     protein localization to chromosome, centromeric region GO:0071459 ISO     protein localization to chromosome, centromeric region GO:0071459 ISS     genomic imprinting GO:0071514 IDA     genomic imprinting GO:0071514 IMP     chromatin looping GO:0140588 IDA     chromatin looping GO:0140588 IMP     chromatin looping GO:0140588 ISO     positive regulation of miRNA transcription GO:1902895 ISO Subcellular Localization     chromosome, centromeric region GO:0000775 ISO     chromosome, centromeric region GO:0000775 ISS     condensed chromosome GO:0000793 IEA     condensed chromosome GO:0000793 ISO     dense fibrillar component GO:0001651 ISO     granular component GO:0001652 ISO     male germ cell nucleus GO:0001673 IDA     nucleus GO:0005634 IBA     nucleus GO:0005634 IDA     nucleus GO:0005634 ISO     nucleoplasm GO:0005654 IEA     nucleoplasm GO:0005654 ISO     nucleolus GO:0005730 IEA     nucleolus GO:0005730 ISO