Gene description for Csf2rb
Gene name colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
Gene symbol Csf2rb
Other names/aliases AI848964
AIC2B
Bc
CDw131
Csf2rb1
Csfgmrb
Il3r
Il3rb
Il3rb1
Il5rb
Species Mus musculus
 Database cross references - Csf2rb
ExoCarta ExoCarta_12983
Vesiclepedia VP_12983
Entrez Gene 12983
UniProt P26955  
 Csf2rb identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Csf2rb
Molecular Function
    cytokine receptor activity GO:0004896 IBA
    cytokine receptor activity GO:0004896 IEA
    protein binding GO:0005515 IPI
    coreceptor activity GO:0015026 ISO
Biological Process
    regulation of cell growth GO:0001558 IGI
    cell surface receptor signaling pathway via JAK-STAT GO:0007259 ISO
    immunoglobulin mediated immune response GO:0016064 IBA
    cytokine-mediated signaling pathway GO:0019221 IBA
    cytokine-mediated signaling pathway GO:0019221 IDA
    interleukin-5-mediated signaling pathway GO:0038043 ISO
    interleukin-3-mediated signaling pathway GO:0038156 ISO
    granulocyte-macrophage colony-stimulating factor signaling pathway GO:0038157 ISO
    positive regulation of leukocyte proliferation GO:0070665 ISO
Subcellular Localization
    plasma membrane GO:0005886 ISO
    external side of plasma membrane GO:0009897 IBA
    membrane GO:0016020 IEA
    granulocyte macrophage colony-stimulating factor receptor complex GO:0030526 ISO
 Experiment description of studies that identified Csf2rb in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Csf2rb
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Rnf41  
Affinity Capture-Western Mus musculus
2 Il3ra  
Affinity Capture-Western Mus musculus
View the network image/svg+xml



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