Gene description for Cmas
Gene name cytidine monophospho-N-acetylneuraminic acid synthetase
Gene symbol Cmas
Other names/aliases AW208911
CMPNeu5Ac
D6Bwg0250e
Species Mus musculus
 Database cross references - Cmas
ExoCarta ExoCarta_12764
Vesiclepedia VP_12764
Entrez Gene 12764
UniProt Q99KK2  
 Cmas identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Cmas
Molecular Function
    N-acylneuraminate cytidylyltransferase activity GO:0008781 IBA
    N-acylneuraminate cytidylyltransferase activity GO:0008781 IDA
    N-acylneuraminate cytidylyltransferase activity GO:0008781 ISO
Biological Process
    N-acetylneuraminate metabolic process GO:0006054 IEA
    N-acetylneuraminate metabolic process GO:0006054 IMP
    CMP-N-acetylneuraminate biosynthetic process GO:0006055 IMP
    CMP-N-acetylneuraminate biosynthetic process GO:0006055 ISO
Subcellular Localization
    nucleus GO:0005634 ISO
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified Cmas in sEVs
1
Experiment ID 15
MISEV standards
✔
EM
Biophysical techniques
✔
CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Cmas
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Kctd13  
Affinity Capture-MS Mus musculus
2 Pou5f1  
Affinity Capture-MS Mus musculus
View the network image/svg+xml



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