Gene description for Apoa2
Gene name	apolipoprotein A-II
Gene symbol	Apoa2
Other names/aliases	Alp-2 Apo-AII ApoA-II ApoAII Apoa-2 Hdl-1
Species	Mus musculus
Database cross references - Apoa2
ExoCarta	ExoCarta_11807
Vesiclepedia	VP_11807
Entrez Gene	11807
UniProt	P09813
Apoa2 identified in sEVs derived from the following tissue/cell type
Faeces	33431899
Faeces	33431899

Gene ontology annotations for Apoa2

Molecular Function     signaling receptor binding GO:0005102 ISO     lipid transporter activity GO:0005319 ISO     phospholipid binding GO:0005543 ISO     high-density lipoprotein particle binding GO:0008035 IBA     high-density lipoprotein particle binding GO:0008035 IMP     lipid binding GO:0008289 ISO     cholesterol binding GO:0015485 IEA     cholesterol binding GO:0015485 ISO     enzyme binding GO:0019899 IEA     enzyme binding GO:0019899 ISO     heat shock protein binding GO:0031072 IEA     heat shock protein binding GO:0031072 ISO     phosphatidylcholine binding GO:0031210 IEA     phosphatidylcholine binding GO:0031210 ISO     apolipoprotein receptor binding GO:0034190 IEA     apolipoprotein receptor binding GO:0034190 ISO     protein homodimerization activity GO:0042803 IEA     protein homodimerization activity GO:0042803 ISO     protein heterodimerization activity GO:0046982 ISO     protein heterodimerization activity GO:0046982 ISS     receptor ligand activity GO:0048018 IEA     lipase inhibitor activity GO:0055102 IEA     lipase inhibitor activity GO:0055102 ISO     phosphatidylcholine-sterol O-acyltransferase activator activity GO:0060228 IEA     phosphatidylcholine-sterol O-acyltransferase activator activity GO:0060228 ISO     high-density lipoprotein particle receptor binding GO:0070653 IEA     high-density lipoprotein particle receptor binding GO:0070653 ISO     cholesterol transfer activity GO:0120020 IEA     cholesterol transfer activity GO:0120020 ISO     cholesterol transfer activity GO:0120020 ISO Biological Process     negative regulation of cytokine production involved in immune response GO:0002719 IEA     negative regulation of cytokine production involved in immune response GO:0002719 ISO     phosphatidylcholine biosynthetic process GO:0006656 IEA     phosphatidylcholine biosynthetic process GO:0006656 ISO     lipid transport GO:0006869 IMP     signal transduction GO:0007165 IEA     cholesterol metabolic process GO:0008203 IGI     cholesterol metabolic process GO:0008203 IMP     phospholipid catabolic process GO:0009395 IEA     phospholipid catabolic process GO:0009395 ISO     response to glucose GO:0009749 IEA     response to glucose GO:0009749 ISO     negative regulation of very-low-density lipoprotein particle remodeling GO:0010903 IEA     negative regulation of very-low-density lipoprotein particle remodeling GO:0010903 ISO     protein oxidation GO:0018158 ISO     peptidyl-methionine modification GO:0018206 ISO     regulation of intestinal cholesterol absorption GO:0030300 IMP     cholesterol transport GO:0030301 IBA     cholesterol transport GO:0030301 ISO     animal organ regeneration GO:0031100 ISO     regulation of protein stability GO:0031647 ISO     negative regulation of cholesterol transport GO:0032375 ISO     positive regulation of interleukin-8 production GO:0032757 ISO     positive regulation of interleukin-8 production GO:0032757 ISS     cholesterol efflux GO:0033344 IEA     cholesterol efflux GO:0033344 ISO     phospholipid efflux GO:0033700 IEA     phospholipid efflux GO:0033700 ISO     triglyceride-rich lipoprotein particle remodeling GO:0034370 IEA     triglyceride-rich lipoprotein particle remodeling GO:0034370 ISO     low-density lipoprotein particle remodeling GO:0034374 IEA     low-density lipoprotein particle remodeling GO:0034374 ISO     high-density lipoprotein particle remodeling GO:0034375 IEA     high-density lipoprotein particle remodeling GO:0034375 ISO     high-density lipoprotein particle assembly GO:0034380 IEA     high-density lipoprotein particle assembly GO:0034380 ISO     high-density lipoprotein particle clearance GO:0034384 IEA     high-density lipoprotein particle clearance GO:0034384 ISO     lipoprotein metabolic process GO:0042157 IDA     cholesterol homeostasis GO:0042632 IBA     cholesterol homeostasis GO:0042632 IDA     cholesterol homeostasis GO:0042632 IGI     cholesterol homeostasis GO:0042632 IMP     cholesterol homeostasis GO:0042632 ISO     reverse cholesterol transport GO:0043691 IEA     reverse cholesterol transport GO:0043691 ISO     diacylglycerol catabolic process GO:0046340 IEA     diacylglycerol catabolic process GO:0046340 ISO     positive regulation of phagocytosis GO:0050766 ISO     positive regulation of phagocytosis GO:0050766 ISS     protein stabilization GO:0050821 ISO     protein stabilization GO:0050821 ISS     negative regulation of lipid catabolic process GO:0050995 IEA     negative regulation of lipid catabolic process GO:0050995 ISO     positive regulation of lipid catabolic process GO:0050996 IEA     positive regulation of lipid catabolic process GO:0050996 ISO     negative regulation of lipase activity GO:0060192 IMP     negative regulation of lipase activity GO:0060192 ISO     negative regulation of cholesterol import GO:0060621 IEA     negative regulation of cholesterol import GO:0060621 ISO     negative regulation of cholesterol transporter activity GO:0060695 ISO     cellular response to lipoprotein particle stimulus GO:0071402 IEA     positive regulation of CoA-transferase activity GO:1905920 ISO Subcellular Localization     extracellular region GO:0005576 TAS     extracellular space GO:0005615 IDA     cytosol GO:0005829 TAS     very-low-density lipoprotein particle GO:0034361 IEA     very-low-density lipoprotein particle GO:0034361 ISO     high-density lipoprotein particle GO:0034364 ISO     spherical high-density lipoprotein particle GO:0034366 IBA     spherical high-density lipoprotein particle GO:0034366 IEA     spherical high-density lipoprotein particle GO:0034366 ISO     chylomicron GO:0042627 IEA     chylomicron GO:0042627 ISO