Gene description for Lamc1
Gene name laminin, gamma 1
Gene symbol Lamc1
Other names/aliases B2e
Species Rattus norvegicus
 Database cross references - Lamc1
ExoCarta ExoCarta_117036
Vesiclepedia VP_117036
Entrez Gene 117036
 Lamc1 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Lamc1
Molecular Function
    extracellular matrix structural constituent GO:0005201 ISO
    glycosphingolipid binding GO:0043208 ISO
Biological Process
    chromatin organization GO:0006325 ISO
    cell adhesion GO:0007155 ISO
    axon guidance GO:0007411 IBA
    animal organ morphogenesis GO:0009887 IBA
    tissue development GO:0009888 IBA
    gene expression GO:0010467 ISO
    cell migration GO:0016477 ISO
    extracellular matrix disassembly GO:0022617 ISO
    hair follicle morphogenesis GO:0031069 ISO
    neuron projection development GO:0031175 ISO
    hemidesmosome assembly GO:0031581 ISO
    substrate adhesion-dependent cell spreading GO:0034446 ISO
    hair cell differentiation GO:0035315 ISO
    tissue morphogenesis GO:0048729 ISO
    protein-containing complex assembly GO:0065003 ISO
    hair follicle cell proliferation GO:0071335 ISO
Subcellular Localization
    basement membrane GO:0005604 IBA
    basement membrane GO:0005604 ISO
    laminin-1 complex GO:0005606 IDA
    neuromuscular junction GO:0031594 ISO
    synaptic cleft GO:0043083 ISO
    laminin-10 complex GO:0043259 ISO
    collagen-containing extracellular matrix GO:0062023 IDA
 Experiment description of studies that identified Lamc1 in sEVs
1
Experiment ID 225
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Lamc1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Klf4  
Reconstituted Complex Rattus norvegicus
Two-hybrid Rattus norvegicus
View the network image/svg+xml
 Pathways in which Lamc1 is involved
No pathways found





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