Gene description for F11r
Gene name F11 receptor
Gene symbol F11r
Other names/aliases Jam1
Species Rattus norvegicus
 Database cross references - F11r
ExoCarta ExoCarta_116479
Vesiclepedia VP_116479
Entrez Gene 116479
UniProt Q9JHY1  
 F11r identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
Reticulocytes 21828046    
 Gene ontology annotations for F11r
Molecular Function
    integrin binding GO:0005178 ISO
    protein binding GO:0005515 IPI
    PDZ domain binding GO:0030165 ISO
    protein homodimerization activity GO:0042803 ISO
Biological Process
    regulation of cytokine production GO:0001817 ISO
    cell adhesion GO:0007155 IEA
    cell adhesion GO:0007155 ISO
    leukocyte cell-cell adhesion GO:0007159 ISO
    regulation of cell shape GO:0008360 ISO
    cell differentiation GO:0030154 IEP
    epithelial cell differentiation GO:0030855 ISO
    actomyosin structure organization GO:0031032 ISO
    regulation of actin cytoskeleton organization GO:0032956 ISO
    positive regulation of Rho protein signal transduction GO:0035025 ISO
    memory T cell extravasation GO:0035683 ISO
    positive regulation of blood pressure GO:0045777 IDA
    intestinal absorption GO:0050892 IBA
    intestinal absorption GO:0050892 ISO
    regulation of cytoskeleton organization GO:0051493 ISO
    negative regulation of stress fiber assembly GO:0051497 ISO
    cellular response to mechanical stimulus GO:0071260 ISO
    protein localization to plasma membrane GO:0072659 ISO
    establishment of endothelial intestinal barrier GO:0090557 IBA
    establishment of endothelial intestinal barrier GO:0090557 ISO
    regulation of membrane permeability GO:0090559 IBA
    regulation of membrane permeability GO:0090559 ISO
    cell-cell adhesion GO:0098609 ISO
    positive regulation of platelet aggregation GO:1901731 ISO
    protein localization to bicellular tight junction GO:1902396 ISO
    positive regulation of establishment of endothelial barrier GO:1903142 ISO
    regulation of bicellular tight junction assembly GO:2000810 ISO
Subcellular Localization
    plasma membrane GO:0005886 IEA
    plasma membrane GO:0005886 ISO
    cell-cell junction GO:0005911 IDA
    bicellular tight junction GO:0005923 IBA
    bicellular tight junction GO:0005923 IEA
    bicellular tight junction GO:0005923 ISO
    protein-containing complex GO:0032991 ISO
    slit diaphragm GO:0036057 IDA
    tight junction GO:0070160 ISO
 Experiment description of studies that identified F11r in sEVs
1
Experiment ID 225
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
2
Experiment ID 97
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP90|HSC70|MHCI
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for F11r
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here