Gene description for F11r
Gene name F11 receptor
Gene symbol F11r
Other names/aliases Jam1
Species Rattus norvegicus
 Database cross references - F11r
ExoCarta ExoCarta_116479
Vesiclepedia VP_116479
Entrez Gene 116479
UniProt Q9JHY1  
 F11r identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
Reticulocytes 21828046    
 Gene ontology annotations for F11r
Molecular Function
    integrin binding GO:0005178 ISO
    protein binding GO:0005515 IPI
    PDZ domain binding GO:0030165 ISO
    protein homodimerization activity GO:0042803 ISO
Biological Process
    regulation of cytokine production GO:0001817 ISO
    cell adhesion GO:0007155 IEA
    cell adhesion GO:0007155 ISO
    leukocyte cell-cell adhesion GO:0007159 ISO
    regulation of cell shape GO:0008360 ISO
    cell differentiation GO:0030154 IEP
    epithelial cell differentiation GO:0030855 ISO
    actomyosin structure organization GO:0031032 ISO
    regulation of actin cytoskeleton organization GO:0032956 ISO
    positive regulation of Rho protein signal transduction GO:0035025 ISO
    memory T cell extravasation GO:0035683 ISO
    positive regulation of blood pressure GO:0045777 IDA
    intestinal absorption GO:0050892 IBA
    intestinal absorption GO:0050892 ISO
    regulation of cytoskeleton organization GO:0051493 ISO
    negative regulation of stress fiber assembly GO:0051497 ISO
    cellular response to mechanical stimulus GO:0071260 ISO
    protein localization to plasma membrane GO:0072659 ISO
    establishment of endothelial intestinal barrier GO:0090557 IBA
    establishment of endothelial intestinal barrier GO:0090557 ISO
    regulation of membrane permeability GO:0090559 IBA
    regulation of membrane permeability GO:0090559 ISO
    cell-cell adhesion GO:0098609 ISO
    positive regulation of platelet aggregation GO:1901731 ISO
    protein localization to bicellular tight junction GO:1902396 ISO
    positive regulation of establishment of endothelial barrier GO:1903142 ISO
    regulation of bicellular tight junction assembly GO:2000810 ISO
Subcellular Localization
    plasma membrane GO:0005886 IEA
    plasma membrane GO:0005886 ISO
    cell-cell junction GO:0005911 IDA
    bicellular tight junction GO:0005923 IBA
    bicellular tight junction GO:0005923 IEA
    bicellular tight junction GO:0005923 ISO
    protein-containing complex GO:0032991 ISO
    slit diaphragm GO:0036057 IDA
    tight junction GO:0070160 ISO
 Experiment description of studies that identified F11r in sEVs
1
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
2
Experiment ID 97
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for F11r
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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