Gene description for Scpep1
Gene name serine carboxypeptidase 1
Gene symbol Scpep1
Other names/aliases Risc
Species Rattus norvegicus
 Database cross references - Scpep1
ExoCarta ExoCarta_114861
Vesiclepedia VP_114861
Entrez Gene 114861
UniProt Q920A6  
 Scpep1 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Scpep1
Molecular Function
    serine-type carboxypeptidase activity GO:0004185 IBA
    serine-type carboxypeptidase activity GO:0004185 IEA
    serine-type carboxypeptidase activity GO:0004185 ISO
    serine-type carboxypeptidase activity GO:0004185 TAS
Biological Process
    proteolysis GO:0006508 IEA
    retinoic acid metabolic process GO:0042573 IEP
    negative regulation of blood pressure GO:0045776 IEA
    negative regulation of blood pressure GO:0045776 ISO
    blood vessel diameter maintenance GO:0097746 IEA
    blood vessel diameter maintenance GO:0097746 ISO
Subcellular Localization
    extracellular region GO:0005576 IEA
 Experiment description of studies that identified Scpep1 in sEVs
1
Experiment ID 96
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Scpep1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Scpep1 is involved
No pathways found





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