Gene description for Ugt1a6
Gene name UDP glucuronosyltransferase 1 family, polypeptide A6
Gene symbol Ugt1a6
Other names/aliases UDPGT 1-6
Udpgt
Ugt1
Ugt1a7
Species Rattus norvegicus
 Database cross references - Ugt1a6
ExoCarta ExoCarta_113992
Vesiclepedia VP_113992
Entrez Gene 113992
UniProt P08430  
 Ugt1a6 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
Hepatocytes 19367702    
 Gene ontology annotations for Ugt1a6
Molecular Function
    retinoic acid binding GO:0001972 ISO
    glucuronosyltransferase activity GO:0015020 IDA
    glucuronosyltransferase activity GO:0015020 IEA
    glucuronosyltransferase activity GO:0015020 ISO
    enzyme binding GO:0019899 IBA
    enzyme binding GO:0019899 ISO
    protein homodimerization activity GO:0042803 ISO
    protein-containing complex binding GO:0044877 IDA
    protein heterodimerization activity GO:0046982 ISO
Biological Process
    liver development GO:0001889 IEP
    xenobiotic metabolic process GO:0006805 ISO
    response to organic cyclic compound GO:0014070 IEP
    4-chlorobiphenyl metabolic process GO:0018880 IDA
    response to lipopolysaccharide GO:0032496 IEP
    cellular response to hormone stimulus GO:0032870 IEP
    response to peptide hormone GO:0043434 IEP
    cellular glucuronidation GO:0052695 IBA
    cellular glucuronidation GO:0052695 ISO
    cellular response to glucocorticoid stimulus GO:0071385 IDA
Subcellular Localization
    endoplasmic reticulum GO:0005783 IBA
    endoplasmic reticulum GO:0005783 ISO
    endoplasmic reticulum membrane GO:0005789 IEA
    protein-containing complex GO:0032991 IDA
    intracellular membrane-bounded organelle GO:0043231 ISO
 Experiment description of studies that identified Ugt1a6 in sEVs
1
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
2
Experiment ID 35
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|CD81|CD63
Enriched markers
HSPA5
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Ugt1a6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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