Gene description for Prdx5
Gene name	peroxiredoxin 5
Gene symbol	Prdx5
Other names/aliases	Aoeb166
Species	Rattus norvegicus
Database cross references - Prdx5
ExoCarta	ExoCarta_113898
Vesiclepedia	VP_113898
Entrez Gene	113898
UniProt	Q9R063
Prdx5 identified in sEVs derived from the following tissue/cell type
Adipocytes	25998041
Urine	20535238

Gene ontology annotations for Prdx5

Molecular Function     RNA polymerase III transcription regulatory region sequence-specific DNA binding GO:0001016 IEA     RNA polymerase III transcription regulatory region sequence-specific DNA binding GO:0001016 ISO     peroxidase activity GO:0004601 ISO     signaling receptor binding GO:0005102 ISO     thioredoxin peroxidase activity GO:0008379 IBA     thioredoxin peroxidase activity GO:0008379 IEA     thioredoxin peroxidase activity GO:0008379 ISO     antioxidant activity GO:0016209 ISO     identical protein binding GO:0042802 ISO     cysteine-type endopeptidase inhibitor activity involved in apoptotic process GO:0043027 IEA     cysteine-type endopeptidase inhibitor activity involved in apoptotic process GO:0043027 ISO     peroxynitrite reductase activity GO:0072541 ISO     thioredoxin-dependent peroxiredoxin activity GO:0140824 ISO Biological Process     response to oxidative stress GO:0006979 ISO     negative regulation of transcription by RNA polymerase III GO:0016480 IEA     negative regulation of transcription by RNA polymerase III GO:0016480 ISO     positive regulation of collagen biosynthetic process GO:0032967 ISO     cellular response to oxidative stress GO:0034599 IBA     cellular response to oxidative stress GO:0034599 IEA     cellular response to reactive oxygen species GO:0034614 IEA     cellular response to reactive oxygen species GO:0034614 ISO     hydrogen peroxide catabolic process GO:0042744 IBA     hydrogen peroxide catabolic process GO:0042744 ISO     negative regulation of apoptotic process GO:0043066 IEA     negative regulation of apoptotic process GO:0043066 ISO     cell redox homeostasis GO:0045454 IBA     negative regulation of oxidoreductase activity GO:0051354 ISO     regulation of apoptosis involved in tissue homeostasis GO:0060785 ISO     NADPH oxidation GO:0070995 ISO     cellular oxidant detoxification GO:0098869 IEA     reactive nitrogen species metabolic process GO:2001057 ISO Subcellular Localization     nucleus GO:0005634 IEA     nucleus GO:0005634 ISO     cytoplasm GO:0005737 IBA     cytoplasm GO:0005737 ISO     mitochondrion GO:0005739 IBA     mitochondrion GO:0005739 IDA     mitochondrion GO:0005739 IEA     mitochondrion GO:0005739 ISO     peroxisome GO:0005777 IBA     peroxisome GO:0005777 IDA     peroxisome GO:0005777 IEA     peroxisome GO:0005777 ISO     peroxisomal matrix GO:0005782 IEA     peroxisomal matrix GO:0005782 ISO     cytosol GO:0005829 IEA     cytosol GO:0005829 ISO     cytoplasmic vesicle GO:0031410 IEA     cytoplasmic vesicle GO:0031410 ISO     intracellular membrane-bounded organelle GO:0043231 ISO     perinuclear region of cytoplasm GO:0048471 IEA     perinuclear region of cytoplasm GO:0048471 ISO