Gene description for Hspa13
Gene name heat shock protein 70 family, member 13
Gene symbol Hspa13
Other names/aliases 1600002I10Rik
AV006182
B230217N24Rik
Stch
Species Mus musculus
 Database cross references - Hspa13
ExoCarta ExoCarta_110920
Vesiclepedia VP_110920
Entrez Gene 110920
UniProt Q8BM72  
 Hspa13 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Hspa13
Molecular Function
    ATP binding GO:0005524 IEA
    ATP hydrolysis activity GO:0016887 IBA
    heat shock protein binding GO:0031072 IBA
    protein folding chaperone GO:0044183 IBA
    ATP-dependent protein folding chaperone GO:0140662 IEA
Biological Process
    protein folding GO:0006457 IEA
    protein refolding GO:0042026 IBA
    chaperone cofactor-dependent protein refolding GO:0051085 IBA
Subcellular Localization
    nucleus GO:0005634 IBA
    cytoplasm GO:0005737 IBA
    endoplasmic reticulum GO:0005783 IEA
    cytosol GO:0005829 IBA
    plasma membrane GO:0005886 IBA
 Experiment description of studies that identified Hspa13 in sEVs
1
Experiment ID 907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Hspa13
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Ubqln1  
Co-fractionation Mus musculus
2 Ubqln2  
Co-fractionation Mus musculus
3 Ubqln4  
Co-fractionation Mus musculus
4 Atg12  
Positive Genetic Mus musculus
5 G3bp2  
Co-fractionation Mus musculus
6 Sumf2  
Co-fractionation Mus musculus
7 Dnajc3  
Co-fractionation Mus musculus
View the network image/svg+xml



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