|
 Gene description for Acat2 |
| Gene name |
acetyl-Coenzyme A acetyltransferase 2 |
| Gene symbol |
Acat2 |
| Other names/aliases |
AW742799
Tcp-1x
Tcp1-rs1 |
| Species |
Mus musculus |
| Database cross references - Acat2 |
| ExoCarta |
ExoCarta_110460 |
| Vesiclepedia |
VP_110460 |
| Entrez Gene |
110460 |
| UniProt |
Q8CAY6
|
| Acat2 identified in sEVs derived from the following tissue/cell type |
|
Colon cancer cells
|
37309723
|
|
Pancreatic cells
|
19351151
|
|
T-cell lymphoma cells
|
37309723
|
| Gene ontology annotations for Acat2 |
|
|
| Experiment description of studies that identified Acat2 in sEVs |
| 1 |
| Experiment ID |
907 |
| MISEV standards |
|
✔
EM
|
Biophysical techniques |
|
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
|
Enriched markers |
|
✔
HSPA5
|
Negative markers |
|
✔
NTA
|
Particle analysis
|
|
| Identified molecule |
Protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
37309723
|
| Organism |
Mus musculus |
| Experiment description |
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells |
| Authors |
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S." |
| Journal name |
Proteomics
|
| Publication year |
2023 |
| Sample |
Colon cancer cells |
| Sample name |
C26 |
| Isolation/purification methods |
Differential centrifugation
Ultracentrifugation |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Western blotting
Mass spectrometry |
|
|
| 2 |
| Experiment ID |
188 |
| MISEV standards |
|
✔
EM
|
Biophysical techniques |
|
✔
GAPDH|UCHL1|HSP90
|
Enriched markers |
|
✘
|
Negative markers |
|
✘
|
Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
19351151
|
| Organism |
Mus musculus |
| Experiment description |
Characterization of vesicles secreted from insulinoma NIT-1 cells. |
| Authors |
"Lee HS, Jeong J, Lee KJ." |
| Journal name |
J Proteome Res
|
| Publication year |
2009 |
| Sample |
Pancreatic cells |
| Sample name |
Pancreatic beta cell (NIT-1) |
| Isolation/purification methods |
Differential centrifugation
Sucrose density gradient |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry |
|
|
| 3 |
| Experiment ID |
908 |
| MISEV standards |
|
✔
EM
|
Biophysical techniques |
|
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
|
Enriched markers |
|
✔
HSPA5
|
Negative markers |
|
✔
NTA
|
Particle analysis
|
|
| Identified molecule |
Protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
37309723
|
| Organism |
Mus musculus |
| Experiment description |
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells |
| Authors |
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S." |
| Journal name |
Proteomics
|
| Publication year |
2023 |
| Sample |
T-cell lymphoma cells |
| Sample name |
EL4 |
| Isolation/purification methods |
Differential centrifugation
Ultracentrifugation |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Western blotting
Mass spectrometry |
|
|
| Protein-protein interactions for Acat2 |
| |
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
|
No interactions are found.
|
|
| Pathways in which Acat2 is involved |
|
|
|
