Gene description for Trmt10a
Gene name tRNA methyltransferase 10A
Gene symbol Trmt10a
Other names/aliases 3110023L08Rik
AA794508
Rg9mtd2
Rnmtd2
Species Mus musculus
 Database cross references - Trmt10a
ExoCarta ExoCarta_108943
Vesiclepedia VP_108943
Entrez Gene 108943
UniProt Q8C1Z8  
 Trmt10a identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Trmt10a
Molecular Function
    tRNA binding GO:0000049 IBA
    tRNA binding GO:0000049 ISO
    tRNA binding GO:0000049 ISS
    tRNA (guanosine(9)-N1)-methyltransferase activity GO:0052905 IEA
    tRNA (guanosine(9)-N1)-methyltransferase activity GO:0052905 ISO
Biological Process
    tRNA N1-guanine methylation GO:0002939 IBA
    tRNA N1-guanine methylation GO:0002939 ISO
    magnesium ion homeostasis GO:0010960 IMP
    tRNA methylation GO:0030488 ISO
    tRNA methylation GO:0030488 ISS
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 ISO
    nucleus GO:0005634 ISS
    nucleoplasm GO:0005654 IBA
    nucleoplasm GO:0005654 ISO
    nucleolus GO:0005730 ISO
    nucleolus GO:0005730 ISS
    cytosol GO:0005829 IBA
    cytosol GO:0005829 ISO
    actin cytoskeleton GO:0015629 ISO
 Experiment description of studies that identified Trmt10a in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Trmt10a
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Trmt10a is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here