Gene description for Atp6v1h
Gene name ATPase, H+ transporting, lysosomal V1 subunit H
Gene symbol Atp6v1h
Other names/aliases 0710001F19Rik
AU022349
CGI-11
SFD
SFDalpha
SFDbeta
VMA13
Species Mus musculus
 Database cross references - Atp6v1h
ExoCarta ExoCarta_108664
Vesiclepedia VP_108664
Entrez Gene 108664
UniProt Q8BVE3  
 Atp6v1h identified in sEVs derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Atp6v1h
Molecular Function
    proton-transporting ATPase activity, rotational mechanism GO:0046961 IEA
Biological Process
    endocytosis GO:0006897 IEA
    endocytosis GO:0006897 ISO
    synaptic vesicle lumen acidification GO:0097401 EXP
    synaptic vesicle lumen acidification GO:0097401 IDA
    synaptic vesicle lumen acidification GO:0097401 IMP
Subcellular Localization
    vacuolar proton-transporting V-type ATPase, V1 domain GO:0000221 ISS
    membrane GO:0016020 ISO
    clathrin-coated vesicle membrane GO:0030665 IEA
    proton-transporting V-type ATPase complex GO:0033176 IDA
    proton-transporting V-type ATPase, V1 domain GO:0033180 ISO
    extrinsic component of synaptic vesicle membrane GO:0098850 IEA
    extrinsic component of synaptic vesicle membrane GO:0098850 ISO
    ATPase complex GO:1904949 ISO
 Experiment description of studies that identified Atp6v1h in sEVs
1
Experiment ID 210
MISEV standards
EM
Biophysical techniques
CD81|FLOT1
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors "Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL."
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Atp6v1h
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Kctd13  
Affinity Capture-MS Mus musculus
2 Pdxdc1  
Co-fractionation Mus musculus
3 Tmem173  
Proximity Label-MS Mus musculus
4 Eed  
Affinity Capture-MS Mus musculus
5 Tfe3  
Affinity Capture-MS Mus musculus
6 Tia1  
Affinity Capture-MS Mus musculus
7 Unk  
Affinity Capture-RNA Mus musculus
8 Fancd2  
Affinity Capture-MS Mus musculus
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