Gene description for ABCC9
Gene name
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
Gene symbol
ABCC9
Other names/aliases
ABC37 ATFB12 CANTU CMD1O SUR2
Species
Homo sapiens
Database cross references - ABCC9
ExoCarta
ExoCarta_10060
Entrez Gene
10060
HGNC
60
MIM
601439
UniProt
O60706
ABCC9 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells
25944692
Urine
19056867
Gene ontology annotations for ABCC9
Experiment description of studies that identified ABCC9 in exosomes
1
Experiment ID
224
ISEV standards
✔
EM|AFM
EV Biophysical techniques
✔
Alix|TSG101
EV Cytosolic markers
✔
CD63|CD81
EV Membrane markers
✔
GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25944692
Organism
Homo sapiens
Experiment description
Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors
Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name
Oncotarget
Publication year
2015
Sample
Neuroblastoma cells
Sample name
SH-SY5Y
Isolation/purification methods
Differential centrifugation Ultracentrifugation OptiPrep density gradient
Flotation density
1.10 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry Western blotting
2
Experiment ID
63
ISEV standards
✘
EV Biophysical techniques
✘
EV Cytosolic markers
✔
AQP2
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
19056867
Organism
Homo sapiens
Experiment description
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name
JASN
Publication year
2009
Sample
Urine
Sample name
Urine - Normal
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [LTQ] Western blotting
Protein-protein interactions for ABCC9
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
EEF1G
1937
Two-hybrid
Homo sapiens
2
KCNJ8
Invitro
Homo sapiens
3
LDHA
3939
Affinity Capture-Western
Homo sapiens
View the network
image/svg+xml
Pathways in which ABCC9 is involved