Gene description for RAB8A
Gene name RAB8A, member RAS oncogene family
Gene symbol RAB8A
Other names/aliases -
Species Bos taurus
 Database cross references - RAB8A
ExoCarta ExoCarta_100125881
Vesiclepedia VP_100125881
Entrez Gene 100125881
UniProt A4FV54  
 RAB8A identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for RAB8A
Molecular Function
    GTPase activity GO:0003924 IEA
    GTP binding GO:0005525 IEA
Biological Process
    vesicle docking involved in exocytosis GO:0006904 IEA
    protein secretion GO:0009306 IEA
    regulation of exocytosis GO:0017157 IEA
    cellular response to insulin stimulus GO:0032869 IEA
    Golgi vesicle fusion to target membrane GO:0048210 IEA
    protein localization to plasma membrane GO:0072659 IEA
    neurotransmitter receptor transport to postsynaptic membrane GO:0098969 IEA
Subcellular Localization
    endosome GO:0005768 IEA
    plasma membrane GO:0005886 IEA
    synaptic vesicle GO:0008021 IEA
    trans-Golgi network transport vesicle GO:0030140 IEA
    dendritic spine GO:0043197 IEA
 Experiment description of studies that identified RAB8A in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RAB8A
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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