Gene description for SLC22A13
Gene name solute carrier family 22 (organic anion/urate transporter), member 13
Gene symbol SLC22A13
Other names/aliases OAT10
OCTL1
OCTL3
ORCTL-3
ORCTL3
Species Homo sapiens
 Database cross references - SLC22A13
ExoCarta ExoCarta_9390
Vesiclepedia VP_9390
Entrez Gene 9390
HGNC 8494
MIM 604047
UniProt Q9Y226  
 SLC22A13 identified in sEVs derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for SLC22A13
Molecular Function
    urate transmembrane transporter activity GO:0015143 IDA
    nicotinate transmembrane transporter activity GO:0090416 EXP
    nicotinate transmembrane transporter activity GO:0090416 IDA
Biological Process
    positive regulation of T cell mediated cytotoxicity directed against tumor cell target GO:0002854 IDA
    urate transport GO:0015747 IDA
    NAD biosynthesis via nicotinamide riboside salvage pathway GO:0034356 TAS
    negative regulation of fatty acid metabolic process GO:0045922 IDA
    transmembrane transport GO:0055085 IEA
    nicotinate transport GO:2001142 IDA
Subcellular Localization
    endoplasmic reticulum GO:0005783 IDA
    Golgi apparatus GO:0005794 IDA
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 TAS
    apical plasma membrane GO:0016324 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified SLC22A13 in sEVs
1
Experiment ID 63
MISEV standards
Biophysical techniques
AQP2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for SLC22A13
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SEMG1 6406
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 SEMG2 6407
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 CCPG1 9236
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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