Gene description for RBP5
Gene name retinol binding protein 5, cellular
Gene symbol RBP5
Other names/aliases CRBP-III
CRBP3
CRBPIII
Species Homo sapiens
 Database cross references - RBP5
ExoCarta ExoCarta_83758
Vesiclepedia VP_83758
Entrez Gene 83758
HGNC 15847
MIM 611866
UniProt P82980  
 RBP5 identified in sEVs derived from the following tissue/cell type
Urine 15326289    
Urine 19056867    
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for RBP5
Molecular Function
    retinoid binding GO:0005501 TAS
    fatty acid binding GO:0005504 IBA
    protein binding GO:0005515 IPI
    retinal binding GO:0016918 IEA
    retinol binding GO:0019841 IEA
Biological Process
    fatty acid transport GO:0015908 IBA
Subcellular Localization
    nucleus GO:0005634 IBA
    cytosol GO:0005829 IBA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified RBP5 in sEVs
1
Experiment ID 13
MISEV standards
IEM
Biophysical techniques
Alix|RAB4|RAB5B|RAB11|TSG101|CD9|AQP2|AQP1
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15326289    
Organism Homo sapiens
Experiment description Identification and proteomic profiling of exosomes in human urine.
Authors "Pisitkun T, Shen RF, Knepper MA"
Journal name PNAS
Publication year 2004
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA XP]
Western blotting
2
Experiment ID 63
MISEV standards
Biophysical techniques
AQP2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
3
Experiment ID 196
MISEV standards
EM
Biophysical techniques
Alix|TSG101|HSP70|CD9
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
4
Experiment ID 197
MISEV standards
EM
Biophysical techniques
Alix|TSG101|HSP70|CD9
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RBP5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 NR0B2  
Two-hybrid Homo sapiens
2 HIST3H3 8290
Reconstituted Complex Homo sapiens
3 CCNDBP1 23582
Two-hybrid Homo sapiens
4 ABCC5 10057
Two-hybrid Homo sapiens
5 AGR2 10551
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which RBP5 is involved
No pathways found





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