Gene description for Actr3
Gene name	ARP3 actin-related protein 3 homolog (yeast)
Gene symbol	Actr3
Other names/aliases	Arp3
Species	Rattus norvegicus
Database cross references - Actr3
ExoCarta	ExoCarta_81732
Vesiclepedia	VP_81732
Entrez Gene	81732
UniProt	Q4V7C7
Actr3 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Actr3

Molecular Function     actin binding GO:0003779 IDA     actin binding GO:0003779 IEA     structural constituent of cytoskeleton GO:0005200 ISO     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     actin filament binding GO:0051015 IBA     actin filament binding GO:0051015 ISO     ATPase binding GO:0051117 IPI Biological Process     establishment or maintenance of cell polarity GO:0007163 IEA     establishment or maintenance of cell polarity GO:0007163 ISO     spermatogenesis GO:0007283 IEP     asymmetric cell division GO:0008356 IEA     asymmetric cell division GO:0008356 ISO     positive regulation of lamellipodium assembly GO:0010592 IMP     positive regulation of lamellipodium assembly GO:0010592 ISO     positive regulation of lamellipodium assembly GO:0010592 ISS     positive regulation of fibroblast migration GO:0010763 IMP     meiotic chromosome movement towards spindle pole GO:0016344 IEA     meiotic chromosome movement towards spindle pole GO:0016344 ISO     negative regulation of axon extension GO:0030517 IMP     positive regulation of actin filament polymerization GO:0030838 IMP     response to estradiol GO:0032355 IEP     regulation of actin cytoskeleton organization GO:0032956 IMP     meiotic cytokinesis GO:0033206 IEA     meiotic cytokinesis GO:0033206 ISO     Arp2/3 complex-mediated actin nucleation GO:0034314 IBA     Arp2/3 complex-mediated actin nucleation GO:0034314 ISO     Arp2/3 complex-mediated actin nucleation GO:0034314 ISS     cellular response to trichostatin A GO:0035984 IEP     regulation of myosin II filament organization GO:0043519 IMP     positive regulation of neuron differentiation GO:0045666 IMP     positive regulation of transcription by RNA polymerase II GO:0045944 ISO     positive regulation of transcription by RNA polymerase II GO:0045944 ISS     astrocyte differentiation GO:0048708 IMP     positive regulation of astrocyte differentiation GO:0048711 IMP     positive regulation of dendrite morphogenesis GO:0050775 IMP     meiotic cell cycle GO:0051321 ISO     positive regulation of filopodium assembly GO:0051491 IMP     spindle localization GO:0051653 IEA     spindle localization GO:0051653 ISO     positive regulation of synapse assembly GO:0051965 IMP     cilium assembly GO:0060271 ISO     cilium assembly GO:0060271 ISS     positive regulation of dendritic spine morphogenesis GO:0061003 IMP     Sertoli cell barrier remodeling GO:0061843 IEP     cellular response to type II interferon GO:0071346 IEA     cellular response to type II interferon GO:0071346 ISO     cellular response to interleukin-1 GO:0071347 IEP     cellular response to tumor necrosis factor GO:0071356 IDA     cellular response to epidermal growth factor stimulus GO:0071364 IEP     response to heparin GO:0071503 IEP     cellular response to transforming growth factor beta stimulus GO:0071560 IDA     positive regulation of protein targeting to membrane GO:0090314 IMP     postsynaptic actin cytoskeleton organization GO:0098974 IDA     postsynaptic actin cytoskeleton organization GO:0098974 IMP     postsynapse organization GO:0099173 IDA     postsynapse organization GO:0099173 IMP     positive regulation of protein localization to plasma membrane GO:1903078 IMP     negative regulation of bleb assembly GO:1904171 IMP     cellular response to pyrimidine ribonucleotide GO:1905835 IEP     cellular response to triterpenoid GO:1905837 IEP Subcellular Localization     Golgi membrane GO:0000139 IDA     ruffle GO:0001726 IDA     podosome GO:0002102 IDA     nucleus GO:0005634 IEA     nucleus GO:0005634 ISO     nucleus GO:0005634 ISS     cytoplasm GO:0005737 ISO     cytoskeleton GO:0005856 IEA     actin filament GO:0005884 IDA     Arp2/3 protein complex GO:0005885 IBA     Arp2/3 protein complex GO:0005885 ISO     Arp2/3 protein complex GO:0005885 ISS     brush border GO:0005903 IEA     brush border GO:0005903 ISO     cell-cell junction GO:0005911 IDA     cell-cell junction GO:0005911 IEA     cell-cell junction GO:0005911 ISO     lamellipodium GO:0030027 IDA     lamellipodium GO:0030027 IEA     lamellipodium GO:0030027 ISO     hemidesmosome GO:0030056 IDA     cell leading edge GO:0031252 IDA     site of double-strand break GO:0035861 ISS     cell projection GO:0042995 IEA     perinuclear region of cytoplasm GO:0048471 IDA     excitatory synapse GO:0060076 IDA     podosome core GO:0061825 IDA     apical tubulobulbar complex GO:0061828 IDA     concave side of sperm head GO:0061830 IDA     apical ectoplasmic specialization GO:0061831 IDA     basal ectoplasmic specialization GO:0061832 IDA     leading edge of lamellipodium GO:0061851 IDA     postsynapse GO:0098794 EXP     postsynapse GO:0098794 IDA     postsynapse GO:0098794 IMP     glutamatergic synapse GO:0098978 IDA     glutamatergic synapse GO:0098978 IMP