Gene description for ARMC5
Gene name armadillo repeat containing 5
Gene symbol ARMC5
Other names/aliases AIMAH2
Species Homo sapiens
 Database cross references - ARMC5
ExoCarta ExoCarta_79798
Vesiclepedia VP_79798
Entrez Gene 79798
HGNC 25781
MIM 615549
UniProt Q96C12  
 ARMC5 identified in sEVs derived from the following tissue/cell type
Urine 21595033    
Urine 21595033    
Urine 21595033    
 Gene ontology annotations for ARMC5
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    in utero embryonic development GO:0001701 IEA
    mesoderm formation GO:0001707 IEA
    anatomical structure morphogenesis GO:0009653 IBA
    adrenal cortex development GO:0035801 IEA
    T cell proliferation GO:0042098 IEA
    CD4-positive, alpha-beta T cell differentiation GO:0043367 IEA
    regulation of steroid biosynthetic process GO:0050810 IEA
    defense response to virus GO:0051607 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IDA
    cytoplasm GO:0005737 IMP
    cytosol GO:0005829 IBA
    cytosol GO:0005829 IDA
    focal adhesion GO:0005925 IDA
    membrane GO:0016020 IEA
 Experiment description of studies that identified ARMC5 in sEVs
1
Experiment ID 193
MISEV standards
EM
Biophysical techniques
CD63|CD9
Enriched markers
PHB
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 194
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 195
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ARMC5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ESPL1  
Affinity Capture-MS Homo sapiens
2 ENKD1  
Two-hybrid Homo sapiens
3 SPAG8  
Two-hybrid Homo sapiens
4 POLR2M  
Affinity Capture-MS Homo sapiens
5 PRR35  
Two-hybrid Homo sapiens
6 USP7 7874
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
7 GTF3C3 9330
Affinity Capture-MS Homo sapiens
8 HSPA8 3312
Affinity Capture-MS Homo sapiens
9 TUBG1 7283
Affinity Capture-MS Homo sapiens
10 RPAP2  
Affinity Capture-MS Homo sapiens
11 ZNHIT2 741
Affinity Capture-MS Homo sapiens
12 GEMIN5 25929
Affinity Capture-MS Homo sapiens
13 IQGAP3 128239
Affinity Capture-MS Homo sapiens
14 MKRN3  
Two-hybrid Homo sapiens
15 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 DXO  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 CNOT2  
Two-hybrid Homo sapiens
18 TLX3  
Two-hybrid Homo sapiens
19 EGFR 1956
Negative Genetic Homo sapiens
20 HSP90AA1 3320
Affinity Capture-Luminescence Homo sapiens
21 DDX58 23586
Affinity Capture-RNA Homo sapiens
22 RIPK4  
Affinity Capture-MS Homo sapiens
23 TBCD 6904
Affinity Capture-MS Homo sapiens
24 APEX1 328
Affinity Capture-RNA Homo sapiens
25 LMO2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 ACACA 31
Positive Genetic Homo sapiens
27 C12orf49  
Negative Genetic Homo sapiens
28 ACSL3 2181
Affinity Capture-MS Homo sapiens
29 SREBF2 6721
Negative Genetic Homo sapiens
30 GLYCTK  
Two-hybrid Homo sapiens
31 HPS3 84343
Affinity Capture-MS Homo sapiens
32 COL8A1 1295
Two-hybrid Homo sapiens
33 KRAS 3845
Negative Genetic Homo sapiens
34 USHBP1  
Two-hybrid Homo sapiens
35 NCAPG2 54892
Affinity Capture-MS Homo sapiens
36 DYNC2H1 79659
Affinity Capture-MS Homo sapiens
37 POLR2A 5430
Affinity Capture-MS Homo sapiens
38 TAF6L 10629
Affinity Capture-MS Homo sapiens
39 AMD1  
Affinity Capture-MS Homo sapiens
40 TUBGCP6 85378
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ARMC5 is involved
No pathways found





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