Gene description for Hnrnpr
Gene name heterogeneous nuclear ribonucleoprotein R
Gene symbol Hnrnpr
Other names/aliases 2610003J05Rik
2610528B01Rik
Hnrpr
Species Mus musculus
 Database cross references - Hnrnpr
ExoCarta ExoCarta_74326
Vesiclepedia VP_74326
Entrez Gene 74326
 Hnrnpr identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Hnrnpr
Molecular Function
    mRNA binding GO:0003729 IBA
    mRNA 3'-UTR binding GO:0003730 ISO
Biological Process
    positive regulation of mRNA catabolic process GO:0061014 ISO
    mRNA destabilization GO:0061157 ISO
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleus GO:0005634 ISO
    nucleoplasm GO:0005654 ISO
    dendrite GO:0030425 ISO
    growth cone GO:0030426 ISO
    axon terminus GO:0043679 ISO
    catalytic step 2 spliceosome GO:0071013 ISO
    ribonucleoprotein complex GO:1990904 IBA
    ribonucleoprotein complex GO:1990904 ISO
 Experiment description of studies that identified Hnrnpr in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Hnrnpr
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 BMPR2 659
Affinity Capture-MS Homo sapiens
2 Tia1  
Affinity Capture-MS Mus musculus
Affinity Capture-Western Mus musculus
3 Kctd13  
Affinity Capture-MS Mus musculus
4 Mapt  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Hnrnpr is involved
No pathways found





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