Gene description for Entpd2
Gene name ectonucleoside triphosphate diphosphohydrolase 2
Gene symbol Entpd2
Other names/aliases Cd39l1
NTPDase2
Species Rattus norvegicus
 Database cross references - Entpd2
ExoCarta ExoCarta_64467
Vesiclepedia VP_64467
Entrez Gene 64467
UniProt O35795  
 Entpd2 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Entpd2
Molecular Function
    GDP phosphatase activity GO:0004382 IBA
    ATP binding GO:0005524 IEA
    hydrolase activity GO:0016787 IEA
    ATP hydrolysis activity GO:0016887 IDA
    nucleoside diphosphate phosphatase activity GO:0017110 IEA
    nucleoside diphosphate phosphatase activity GO:0017110 ISO
    ribonucleoside triphosphate phosphatase activity GO:0017111 IBA
    ribonucleoside triphosphate phosphatase activity GO:0017111 IEA
    ribonucleoside triphosphate phosphatase activity GO:0017111 ISO
    identical protein binding GO:0042802 IPI
    ADP phosphatase activity GO:0043262 IDA
    UDP phosphatase activity GO:0045134 IBA
Biological Process
    G protein-coupled receptor signaling pathway GO:0007186 IEA
    G protein-coupled receptor signaling pathway GO:0007186 ISO
    nucleoside diphosphate catabolic process GO:0009134 IBA
    purine ribonucleoside diphosphate catabolic process GO:0009181 IEA
    purine ribonucleoside diphosphate catabolic process GO:0009181 ISO
    response to auditory stimulus GO:0010996 IEP
    platelet activation GO:0030168 IEA
    platelet activation GO:0030168 ISO
    cellular response to interferon-alpha GO:0035457 IEP
    cellular response to lipopolysaccharide GO:0071222 IEP
    cellular response to interleukin-6 GO:0071354 IMP
    cellular response to tumor necrosis factor GO:0071356 IEP
Subcellular Localization
    basement membrane GO:0005604 IEA
    basement membrane GO:0005604 ISO
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IEA
    plasma membrane GO:0005886 ISO
    cell surface GO:0009986 IDA
    membrane GO:0016020 IEA
    cell projection membrane GO:0031253 IDA
    cell body GO:0044297 IDA
 Experiment description of studies that identified Entpd2 in sEVs
1
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Entpd2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here