Gene description for Basp1
Gene name brain abundant, membrane attached signal protein 1
Gene symbol Basp1
Other names/aliases NAP22
Species Rattus norvegicus
 Database cross references - Basp1
ExoCarta ExoCarta_64160
Vesiclepedia VP_64160
Entrez Gene 64160
UniProt Q05175  
 Basp1 identified in sEVs derived from the following tissue/cell type
Urine 20535238    
 Gene ontology annotations for Basp1
Molecular Function
    transcription cis-regulatory region binding GO:0000976 IBA
    transcription cis-regulatory region binding GO:0000976 IEA
    transcription cis-regulatory region binding GO:0000976 ISO
    transcription cis-regulatory region binding GO:0000976 ISS
    transcription corepressor activity GO:0003714 IBA
    transcription corepressor activity GO:0003714 IEA
    transcription corepressor activity GO:0003714 ISO
    transcription corepressor activity GO:0003714 ISS
    calmodulin binding GO:0005516 IEA
    calmodulin binding GO:0005516 ISO
    protein domain specific binding GO:0019904 IEA
    protein domain specific binding GO:0019904 ISO
Biological Process
    substantia nigra development GO:0021762 ISO
    negative regulation of DNA-templated transcription GO:0045892 IBA
    negative regulation of DNA-templated transcription GO:0045892 IEA
    negative regulation of DNA-templated transcription GO:0045892 ISO
    negative regulation of DNA-templated transcription GO:0045892 ISS
    protein homooligomerization GO:0051260 IEA
    protein homooligomerization GO:0051260 ISO
    podocyte differentiation GO:0072112 IEA
    podocyte differentiation GO:0072112 ISO
    supramolecular fiber organization GO:0097435 IEA
    supramolecular fiber organization GO:0097435 ISO
Subcellular Localization
    chromatin GO:0000785 IEA
    chromatin GO:0000785 ISO
    nucleus GO:0005634 IBA
    nucleus GO:0005634 ISO
    nucleus GO:0005634 ISS
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    cytoplasm GO:0005737 IEA
    cytoplasm GO:0005737 ISO
    cytoplasm GO:0005737 ISS
    plasma membrane GO:0005886 IEA
    plasma membrane GO:0005886 ISO
    COP9 signalosome GO:0008180 IEA
    COP9 signalosome GO:0008180 ISO
    nuclear matrix GO:0016363 IEA
    nuclear matrix GO:0016363 ISO
    PML body GO:0016605 IEA
    PML body GO:0016605 ISO
    nuclear speck GO:0016607 IEA
    nuclear speck GO:0016607 ISO
    nuclear speck GO:0016607 ISS
    cell junction GO:0030054 IEA
    cell junction GO:0030054 ISO
    growth cone GO:0030426 IEA
 Experiment description of studies that identified Basp1 in sEVs
1
Experiment ID 192
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20535238    
Organism Rattus norvegicus
Experiment description Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Gonzalez E, Berisa A, Gil D, Embade N, Valle M, Luka Z, Elortza F, Wagner C, Lu SC, Mato JM, Falcon-Perez M."
Journal name Proteomics Clin Appl
Publication year 2010
Sample Urine
Sample name Urine - Rats of liver injury
Isolation/purification methods Differential centrifugation
Filtration
UltracentrifugationSucrose cushion
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Basp1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Snca  
Affinity Capture-MS Rattus norvegicus
2 Itm2b 290364
Affinity Capture-MS Rattus norvegicus
3 Park7 117287
Affinity Capture-MS Rattus norvegicus
View the network image/svg+xml



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