Gene description for Abcb9
Gene name ATP-binding cassette, subfamily B (MDR/TAP), member 9
Gene symbol Abcb9
Other names/aliases Tapl
Species Rattus norvegicus
 Database cross references - Abcb9
ExoCarta ExoCarta_63886
Vesiclepedia VP_63886
Entrez Gene 63886
UniProt Q9QYJ4  
 Abcb9 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
Reticulocytes 21828046    
Reticulocytes 21828046    
 Gene ontology annotations for Abcb9
Molecular Function
    ATP binding GO:0005524 IEA
    ATP binding GO:0005524 ISO
    ABC-type oligopeptide transporter activity GO:0015421 ISO
    ABC-type oligopeptide transporter activity GO:0015421 ISS
    ABC-type peptide transporter activity GO:0015440 IBA
    ABC-type peptide transporter activity GO:0015440 IEA
    ABC-type peptide transporter activity GO:0015440 ISO
    ATP hydrolysis activity GO:0016887 IEA
    transmembrane transporter activity GO:0022857 ISO
    ATPase-coupled transmembrane transporter activity GO:0042626 TAS
    protein homodimerization activity GO:0042803 ISO
Biological Process
    antigen processing and presentation of peptide antigen via MHC class I GO:0002474 ISO
    peptide metabolic process GO:0006518 ISO
    peptide metabolic process GO:0006518 ISS
    biological_process GO:0008150 ND
    protein transport GO:0015031 IEA
    peptide transport GO:0015833 IEA
    peptide transport GO:0015833 ISO
    peptide transport GO:0015833 ISS
    oligopeptide transmembrane transport GO:0035672 IEA
    transmembrane transport GO:0055085 IBA
    transmembrane transport GO:0055085 IEA
Subcellular Localization
    lysosome GO:0005764 ISO
    lysosome GO:0005764 ISS
    lysosomal membrane GO:0005765 IEA
    lysosomal membrane GO:0005765 ISO
    lysosomal membrane GO:0005765 ISS
    early endosome GO:0005769 ISO
    endoplasmic reticulum GO:0005783 ISO
    endoplasmic reticulum membrane GO:0005789 ISO
    membrane GO:0016020 IBA
    membrane GO:0016020 ISO
    ATP-binding cassette (ABC) transporter complex GO:0043190 TAS
    intracellular membrane-bounded organelle GO:0043231 ISO
 Experiment description of studies that identified Abcb9 in sEVs
1
Experiment ID 90
MISEV standards
✔
EM
Biophysical techniques
✔
HSC70|HSP90|TSG101|MHCI
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E"
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
2
Experiment ID 94
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP90|HSC70|MHCI
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
3
Experiment ID 99
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP90|HSC70|MHCI
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [QSTAR]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Abcb9
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Abcb9 is involved
PathwayEvidenceSource
ABC-family proteins mediated transport IEA Reactome
Transport of small molecules IEA Reactome





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