Gene description for TSNAXIP1
Gene name translin-associated factor X interacting protein 1
Gene symbol TSNAXIP1
Other names/aliases TXI1
Species Homo sapiens
 Database cross references - TSNAXIP1
ExoCarta ExoCarta_55815
Vesiclepedia VP_55815
Entrez Gene 55815
HGNC 18586
MIM 607720
UniProt Q2TAA8  
 TSNAXIP1 identified in sEVs derived from the following tissue/cell type
Melanoma cells 15478216    
 Gene ontology annotations for TSNAXIP1
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    spermatogenesis GO:0007283 IEA
    cell differentiation GO:0030154 IEA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    perinuclear region of cytoplasm GO:0048471 IEA
 Experiment description of studies that identified TSNAXIP1 in sEVs
1
Experiment ID 12
MISEV standards
EM
Biophysical techniques
MHCI
Enriched markers
CANX|cytochrome c
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15478216    
Organism Homo sapiens
Experiment description Proteomic analysis of melanoma-derived exosomes by two-dimensional polyacrylamide gel electrophoresis and mass spectrometry.
Authors "Mears R, Craven RA, Hanrahan S, Totty N, Upton C, Young SL, Patel P, Selby PJ, Banks RE"
Journal name PROTEOMICS
Publication year 2004
Sample Melanoma cells
Sample name MeWo
SK-MEL-28
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [4700 Proteomics Analyzer]
Western blotting
 Protein-protein interactions for TSNAXIP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 APP 351
Reconstituted Complex Homo sapiens
2 CCDC186 55088
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 UBE2L3 7332
Co-fractionation Homo sapiens
4 PRPF6 24148
Two-hybrid Homo sapiens
5 SNW1 22938
Two-hybrid Homo sapiens
6 DPP8 54878
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 Dusp14  
Two-hybrid Mus musculus
8 FAM161B  
Two-hybrid Homo sapiens
9 HSPB1 3315
Two-hybrid Homo sapiens
10 FBXW5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 PIBF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 PRPF18  
Two-hybrid Homo sapiens
13 USO1 8615
Affinity Capture-MS Homo sapiens
14 UTP6  
Two-hybrid Homo sapiens
15 DDX58 23586
Affinity Capture-RNA Homo sapiens
16 LZTFL1 54585
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which TSNAXIP1 is involved
No pathways found





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