Gene description for Tenm3
Gene name teneurin transmembrane protein 3
Gene symbol Tenm3
Other names/aliases 2610100B16Rik
Odz1
Odz3
Ten-m3
mKIAA1455
Species Mus musculus
 Database cross references - Tenm3
ExoCarta ExoCarta_23965
Vesiclepedia VP_23965
Entrez Gene 23965
 Tenm3 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Tenm3
Molecular Function
    protein binding GO:0005515 IPI
    identical protein binding GO:0042802 IPI
    protein homodimerization activity GO:0042803 IDA
    protein homodimerization activity GO:0042803 IDA
    protein heterodimerization activity GO:0046982 IBA
    protein heterodimerization activity GO:0046982 IDA
    cell adhesion molecule binding GO:0050839 IBA
Biological Process
    homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 IDA
    signal transduction GO:0007165 IEA
    positive regulation of neuron projection development GO:0010976 IDA
    positive regulation of neuron projection development GO:0010976 IMP
    cell differentiation GO:0030154 IEA
    camera-type eye morphogenesis GO:0048593 ISO
    neuron development GO:0048666 IBA
    synaptic membrane adhesion GO:0099560 IDA
    regulation of homophilic cell adhesion GO:1903385 IDA
    regulation of homophilic cell adhesion GO:1903385 IDA
Subcellular Localization
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 ISS
    membrane GO:0016020 IDA
    axon GO:0030424 IEA
    neuron projection GO:0043005 IBA
    presynaptic active zone membrane GO:0048787 IDA
    glutamatergic synapse GO:0098978 IDA
 Experiment description of studies that identified Tenm3 in sEVs
1
Experiment ID 907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Tenm3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MTNR1B  
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which Tenm3 is involved
No pathways found





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