Gene description for Coro1b
Gene name coronin, actin binding protein 1B
Gene symbol Coro1b
Other names/aliases -
Species Mus musculus
 Database cross references - Coro1b
ExoCarta ExoCarta_23789
Vesiclepedia VP_23789
Entrez Gene 23789
UniProt Q9WUM3  
 Coro1b identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Coro1b
Molecular Function
    protein binding GO:0005515 IPI
    cytoskeletal protein binding GO:0008092 ISO
    identical protein binding GO:0042802 IEA
    identical protein binding GO:0042802 ISO
    protein-containing complex binding GO:0044877 ISO
    actin filament binding GO:0051015 IBA
    actin filament binding GO:0051015 IEA
    actin filament binding GO:0051015 ISO
    Arp2/3 complex binding GO:0071933 IEA
    Arp2/3 complex binding GO:0071933 ISO
Biological Process
    actin filament organization GO:0007015 IBA
    cell migration GO:0016477 IBA
    cell migration GO:0016477 ISO
    actin cytoskeleton organization GO:0030036 ISO
    ruffle organization GO:0031529 IEA
    ruffle organization GO:0031529 ISO
    negative regulation of Arp2/3 complex-mediated actin nucleation GO:0034316 IEA
    negative regulation of Arp2/3 complex-mediated actin nucleation GO:0034316 ISO
    endothelial cell chemotaxis GO:0035767 IEA
    endothelial cell chemotaxis GO:0035767 ISO
    cellular response to platelet-derived growth factor stimulus GO:0036120 IEA
    cellular response to platelet-derived growth factor stimulus GO:0036120 ISO
    wound healing GO:0042060 IEA
    wound healing GO:0042060 ISO
    actin filament bundle assembly GO:0051017 IEA
    actin filament bundle assembly GO:0051017 ISO
    protein kinase C signaling GO:0070528 ISO
    negative regulation of smooth muscle cell chemotaxis GO:0071672 IEA
    negative regulation of smooth muscle cell chemotaxis GO:0071672 ISO
    actin filament branching GO:0090135 IEA
    actin filament branching GO:0090135 ISO
    protein localization to cell leading edge GO:1902463 IEA
    protein localization to cell leading edge GO:1902463 ISO
    negative regulation of lamellipodium morphogenesis GO:2000393 ISO
    positive regulation of lamellipodium morphogenesis GO:2000394 IEA
    positive regulation of lamellipodium morphogenesis GO:2000394 ISO
Subcellular Localization
    stress fiber GO:0001725 IEA
    stress fiber GO:0001725 ISO
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    actin filament GO:0005884 IEA
    actin filament GO:0005884 ISO
    plasma membrane GO:0005886 IEA
    plasma membrane GO:0005886 ISO
    lamellipodium GO:0030027 IEA
    lamellipodium GO:0030027 ISO
    cell leading edge GO:0031252 ISO
    synapse GO:0045202 IDA
    perinuclear region of cytoplasm GO:0048471 IEA
    perinuclear region of cytoplasm GO:0048471 ISO
    cell periphery GO:0071944 ISO
    glutamatergic synapse GO:0098978 IDA
 Experiment description of studies that identified Coro1b in sEVs
1
Experiment ID 907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Coro1b
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Eed  
Affinity Capture-MS Mus musculus
2 Mycbp2 105689
Affinity Capture-MS Mus musculus
3 Kctd13  
Affinity Capture-MS Mus musculus
4 Traf3  
Proximity Label-MS Mus musculus
View the network image/svg+xml
 Pathways in which Coro1b is involved
No pathways found





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