Experiment description of studies that identified ELK4 in sEVs

1 Experiment ID 226 MISEV standards ✔ EM Biophysical techniques ✔ GAPDH|CD9|FLOT1 Enriched markers ✔ LMNA|H2AFX|ATP5A1|TOMM20 Negative markers ✘ Particle analysis Identified molecule mRNA Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa) PubMed ID 26027894     Organism Homo sapiens Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting" Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar" Journal name Journal of Extracellular Vesicles Publication year 2015 Sample Endothelial cells Sample name HMEC-1 Isolation/purification methods Differential ultracentrifugation Sucrose density gradient Flotation density 1.10 g/mL Molecules identified in the study miRNA Protein snoRNA lncRNA yRNA snRNA mRNA ncRNA mtRNA vtRNA scaRNA lincRNA Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa) Western blotting

Protein-protein interactions for ELK4

Protein Interactor ExoCarta ID Identification method PubMed Species 1 BLM 641 Synthetic Growth Defect Homo sapiens 2 SRF   Two-hybrid Homo sapiens Co-crystal Structure Homo sapiens 3 BRCA1 672 Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 4 DOK4 55715 Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Co-localization Homo sapiens Affinity Capture-Western Homo sapiens 5 MAPK3 5595 Biochemical Activity Homo sapiens 6 MAPK8 5599 Biochemical Activity Homo sapiens 7 ELAVL1 1994 Affinity Capture-RNA Homo sapiens 8 MUS81   Synthetic Growth Defect Homo sapiens 9 GRPEL1 80273 Proximity Label-MS Homo sapiens 10 Kifc1   Affinity Capture-MS Mus musculus 11 HNRNPUL1 11100 Affinity Capture-MS Homo sapiens View the network

Pathways in which ELK4 is involved

No pathways found